...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Perinatal Medicine >Evaluation of a strategy to limit blood donor exposure in high risk premature newborns based on clinical estimation of transfusion need.
【24h】

Evaluation of a strategy to limit blood donor exposure in high risk premature newborns based on clinical estimation of transfusion need.

机译：根据对输血需求的临床评估，评估限制高危早产新生儿供血者接触策略的方法。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES: Reservation of dedicated series of pedipacks, consisting of 3 to 4 units of 70 ml filtered red cell concentrate in additive solution SAGM from 1 donor, may reduce donor exposure. In this prospective efficacy study the benefits, release and expiration of pedipacks (PP) assigned to preterm infants requiring neonatal intensive care are analyzed. METHODS: On the basis of clinical assessment of the need for multiple transfusions, 96 preterm neonates (gestational age < 32 wks and/or birth weight < 1500 g) were assigned to either the high risk group (HRG), who were to receive dedicated donor blood units, or the low risk group (LRG). Inclusion criteria for HRG were 1) estimated time of admission > 21 days and 2) expected need for multiple transfusions due to clinical cardiorespiratory instability, prolonged parental feeding or frequent blood sampling. To reduce wastage of donor blood, dedication of donor blood units was limited to 21 days. RESULTS: 50 series (192 PP) were assigned to 42 HRG infants. Two HRG infants received 3 series, 4 received 2 series and 36 received 1 series of PP. Mean transfusion rate was 3.1 PP in the HRG and 0.4 in the LRG. In the LRG 35 of 54 were not transfused, 19 received 1 to 2 PP. In both groups transfused newborns were exposed to 1.1 donors in average. In the HRG of 192 PP, 137 PP (71%) were used within 21 days, and another 30 (16%) before the expiration date < 35 days. Twenty five PP (13%) expired, mainly because of logistical problems in the introduction phase. CONCLUSION: Assignment of dedicated PP on the basis of clinical parameters at entry considerably reduces donor exposure in HRG. Wastage of dedicated blood transfusions was reduced by limitation of the dedicated period (21 days). In terms of efficacy, reservation and use of PP can be optimized by standardized administrative measures.
机译：目的：保留专用系列的脚踏背包，包括3到4个70 ml过滤的红细胞浓缩液和来自1个供体的添加剂溶液SAGM，可以减少供体的暴露。在这项前瞻性疗效研究中，分析了分配给需要新生儿重症监护的早产儿使用的小推车（PP）的益处，释放和有效期。方法：根据对多次输血需求的临床评估，将96例早产儿（胎龄<32 wks和/或出生体重<1500 g）分入高危组（HRG），他们将接受专门的干预。供血单位或低危人群（LRG）。 HRG的纳入标准为1）估计入院时间> 21天，以及2）预期由于临床心肺不稳定，长时间父母喂养或频繁采血而需要多次输血。为了减少献血者的血液浪费，献血者血液单位的专用时间限制为21天。结果：将50个系列（192个PP）分配给42个HRG婴儿。 2名HRG婴儿接受了3个系列，4个接受了2个系列，36个接受了1个系列的PP。在HRG中平均输血率为3.1 PP，在LRG中为0.4。在LRG中，没有输血的有35个，其中19个接受了1至2个PP。在两组中，输血新生儿平均接触1.1个供体。在192 PP的HRG中，在21天之内使用了137 PP（71％），在到期日<35天之前又使用了30 PP（16％）。 25个PP（13％）已过期，主要是由于引入阶段的后勤问题。结论：根据入院时的临床参数分配专用PP可大大减少HRG患者的供体暴露。通过限制专用期限（21天）可以减少专用输血的浪费。在功效方面，可以通过标准化的管理措施来优化PP的保留和使用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号