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首页> 外文期刊>Journal of Perinatal Medicine >Maternal serum interleukin 6 levels in preterm labor: prediction of admission-to-delivery interval.
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Maternal serum interleukin 6 levels in preterm labor: prediction of admission-to-delivery interval.

机译：早产中孕妇血清白细胞介素6的水平：预测分娩间隔。

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OBJECTIVE: To evaluate the diagnostic value of maternal serum interleukin 6 (IL-6), C-reactive protein (CRP) levels and white blood cell (WBC) count for the prediction of preterm labor and length of admission-to-delivery interval in patients with preterm labor. METHODS: Maternal serum IL-6, CRP and WBC count were prospectively determined in eighty-two patients in preterm labor and 21 controls. Data was analyzed in study and control groups, and for the assessment of clinical and laboratory risk factors in the prediction of admission-to-delivery interval in the study group. RESULTS: Maternal serum IL-6 levels were significantly higher in the study group than controls. The IL-6 value associated with the highest percent of true positives and true negatives for the prediction of preterm labor was 5 pg/ml. The area under curve of maternal IL-6 was significantly higher than the area under curve of of CRP and WBC count. In the study group maternal serum IL-6 levels were significantly higher in patients delivered within 2 and 7 days than the nondelivering ones and a cut off value of 8.3 pg/ml was determined for estimation of preterm delivery. CONCLUSION: Maternal serum IL-6 is a reliable marker in the prediction and management of preterm labor and delivery.
机译：目的：评估母体血清白细胞介素6（IL-6），C反应蛋白（CRP）水平和白细胞（WBC）计数对预测早产和分娩时间的诊断价值。有早产的患者。方法：前瞻性测定了82例早产患者和21例对照者的孕妇血清IL-6，CRP和WBC计数。在研究和对照组中分析数据，并在研究组中预测入院与分娩间隔时评估临床和实验室风险因素。结果：研究组孕妇血清IL-6水平明显高于对照组。与预测早产的真阳性和真阴性最高百分比相关的IL-6值为5 pg / ml。孕妇IL-6曲线下面积显着高于CRP和WBC计数曲线下面积。在研究组中，在2天和7天内分娩的患者的孕妇血清IL-6水平显着高于未分娩的患者，确定早产的分界值为8.3 pg / ml。结论：孕妇血清IL-6是预测和管理早产和分娩的可靠标志物。

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