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首页> 外文期刊>Journal of Periodontology >Histomorphometrical analysis of bone formed after maxillary sinus floor augmentation by grafting with a combination of autogenous bone and demineralized freeze-dried bone allograft or hydroxyapatite.
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Histomorphometrical analysis of bone formed after maxillary sinus floor augmentation by grafting with a combination of autogenous bone and demineralized freeze-dried bone allograft or hydroxyapatite.

机译：通过结合自体骨和脱矿冻干骨同种异体移植物或羟基磷灰石进行嫁接，对上颌窦底底板增大后形成的骨进行组织形态计量学分析。

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BACKGROUND: Maxillary sinus floor augmentation procedures are currently the treatment of choice when the alveolar crest of the posterior maxilla is insufficient for dental implant anchorage. This procedure aims to obtain enough bone with biomaterial association with the autogenous bone graft to create volume and allow osteoconduction. The objective of this study was to histologically and histometrically evaluate the bone formed after maxillary sinus floor augmentation by grafting with a combination of autogenous bone, from the symphyseal area mixed with DFDBA or hydroxyapatite. METHODS: Ten biopsies were taken from 10 patients 10 months after sinus floor augmentation using a combination of 50% autogenous bone plus 50% demineralized freeze-dried bone allograft (DFDBA group) or 50% autogenous bone plus 50% hydroxyapatite (HA group). Routine histological processing and staining with hematoxylin and eosin and Masson's trichrome were performed. RESULTS: The histomorphometrical analysis indicated good regenerative results in both groups for the bone tissue mean in the grafted area (50.46+/-16.29% for the DFDBA group and 46.79+/-8.56% for the HA group). Histological evaluation revealed the presence of mature bone with compact and cancellous areas in both groups. The inflammatory infiltrate was on average nonsignificant and of mononuclear prevalence. Some biopsies showed blocks of the biomaterial in the medullary spaces close to the bone wall, with absence of osteogenic activity. CONCLUSIONS: The results indicated that both DFDBA and HA associated with an autogenous bone graft were biocompatible and promoted osteoconduction, acting as a matrix for bone formation. However, both materials were still present after 10 months.
机译：背景：当上颌后牙的牙槽c不足以种植牙固定时，上颌窦底隆突术目前是首选治疗方法。该程序旨在获得与自体骨移植物具有生物材料关联的足够的骨骼，以产生体积并允许骨传导。这项研究的目的是组织学上和组织学上评估自上颌窦底底板增生后形成的骨，方法是将自体骨与来自DFDBA或羟基磷灰石混合的自体骨移植。方法：使用50％自体骨+ 50％脱矿质冻干骨同种异体移植物（DFDBA组）或50％自体骨+ 50％羟基磷灰石（HA组）组合，从窦底隆起术后10个月的10例患者中进行十次活检。进行常规的组织学处理，并用苏木精和曙红和Masson三色染色。结果：组织形态计量学分析表明，两组移植物区域的骨组织平均值均具有良好的再生结果（DFDBA组为50.46 +/- 16.29％，HA组为46.79 +/- 8.56％）。组织学评估显示两组均存在具有致密和松质区域的成熟骨。炎症浸润平均无统计学意义，单核细胞感染率高。一些活检显示在靠近骨壁的髓腔中存在生物材料的阻滞，没有成骨活性。结论：结果表明，DFDFA和HA与自体骨移植物相关，均具有生物相容性并促进骨传导，可作为骨形成的基质。但是，两种材料在10个月后仍然存在。

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