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首页> 外文期刊>Clinics in dermatology >Cutaneous sarcoidosis: differential diagnosis.
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Cutaneous sarcoidosis: differential diagnosis.

机译：皮肤结节病：鉴别诊断。

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摘要

Sarcoidosis is a multisystem disease with cutaneous lesions present in 20%-35% of patients. Given the wide variability of clinical manifestations, it is one of the "great imitators," making it necessary to consider clinical, epidemiological, radiographic, laboratory, and histopathological criteria to make the diagnosis. Cutaneous lesions have been classified as specific and nonspecific, depending on the presence of noncaseating granulomas on histologic studies. Specific lesions include maculopapules, plaques, nodules, lupus pernio, scar infiltration, alopecia, ulcerative lesions, and hypopigmentation among others. Nail, mucosal, and childhood sarcoidosis represent a distinct subset of the disease process. The most common nonspecific lesion is erythema nodosum. Others include calcifications, prurigo, erythema multiforme, nail clubbing, and Sweet syndrome. The importance of considering cutaneous sarcoidosis in the clinical differential diagnosis of a given skin lesion relies on the association with systemic involvement and the convenience of the skin as a tissue source for histologic analysis.
机译：结节病是一种多系统疾病，在20％-35％的患者中存在皮肤病变。鉴于临床表现的广泛差异，它是“伟大的模仿者”之一，因此有必要考虑临床，流行病学，影像学，实验室和组织病理学标准以进行诊断。根据组织学研究中非干酪样肉芽肿的存在，皮肤病变已分为特异性和非特异性。具体的病变包括黄斑，斑块，结节，狼疮，疤痕浸润，脱发，溃疡性病变和色素沉着不足。指甲，粘膜和儿童结节病是疾病过程的一个独特子集。最常见的非特异性病变是结节性红斑。其他包括钙化，瘙痒，多形性红斑，指甲棍和Sweet综合症。在给定皮肤病变的临床鉴别诊断中考虑皮肤结节病的重要性取决于与全身性累及的关联以及皮肤作为组织学分析的组织来源的便利性。

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