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首页> 外文期刊>Clinics in dermatology >Improved efficacy in onychomycosis therapy
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Improved efficacy in onychomycosis therapy

机译：提高甲癣治疗的功效

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摘要

The success rate of onychomycosis treatment is limited by several factors, including the access of the therapeutic agent to the fungal mass, the presence of conidia, and the susceptibility of the different infectious agents to the antifungals. Different strategies used to improve efficacy of the currently available antifungal treatments, their rationale, and the published evidence of their beneficial effects are reviewed. An improved efficacy was demonstrated for some of these strategies, such as combined oral and topical antifungal therapies, whereas most of them lack clear and direct evidence of an increase in therapeutic success.
机译：甲癣治疗的成功率受到几个因素的限制，包括治疗剂进入真菌团块，分生孢子的存在以及不同感染剂对抗真菌药的敏感性。本文回顾了用于提高当前可用抗真菌治疗功效的不同策略，其原理以及已发表的有益效果的证据。对于其中一些策略，例如口服和局部抗真菌治疗的组合，已证明其疗效有所提高，而其中大多数都缺乏明确和直接的证据表明治疗成功率提高。

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