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首页> 外文期刊>Journal of Photochemistry and Photobiology, B. Biology: Official Journal of the European Society for Photobiology >Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits
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Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits

机译:鼻内光疗对家兔鼻黏膜影响的组织病理学评价

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摘要

Allergic rhinitis is a high-incidence allergic inflammation of the nasal airways that impacts quality of life. Of the numerous therapies used to treat allergic rhinitis, intranasal phototherapy has emerged as a promising new treatment modality for inflammatory airway disease. Phototherapy is widely used for the treatment of immune-mediated skin diseases because its profound immunosuppressive effect inhibits hypersensitivity reactions in the skin. Intranasal phototherapy using a combination of Ultraviolet-A (UVA) and Ultraviolet-B (UVB) plus Visible light (VIS) has been shown to suppress the clinical symptoms of allergic rhinitis, but limited data regarding its adverse effects on the nasal mucosa currently exists. In this study, we demonstrate that UV displays no harmful effects on the nasal mucosa cells of rabbits following 2 weeks of intranasal phototherapy.
机译:过敏性鼻炎是鼻气的高发性过敏性炎症,会影响生活质量。在用于治疗变应性鼻炎的众多疗法中,鼻内光疗已成为炎症性气道疾病的一种有希望的新治疗方式。光疗由于其深刻的免疫抑制作用抑制了皮肤的超敏反应,因此被广泛用于治疗免疫介导的皮肤疾病。结合使用紫外线A(UVA)和紫外线B(UVB)加上可见光(VIS)进行的鼻内光疗可抑制变应性鼻炎的临床症状,但有关其对鼻黏膜不良影响的数据有限。在这项研究中,我们证明了经鼻内光疗2周后,紫外线对兔子的鼻黏膜细胞没有有害作用。

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