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Acute pancreatitis induced by ifosfamide therapy.

机译:异环磷酰胺治疗引起的急性胰腺炎。

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摘要

Ifosfamide used in the treatment of pediatric solid tumors is known to have serious adverse effects, including acute pancreatitis, a rare complication of therapy. This report describes a young girl who developed acute pancreatitis while being treated for recurrent Wilms tumor with the ifosfamide, carboplatin, and etoposide regimen. She recovered completely and without sequelae from ifosfamide-induced pancreatitis soon after the drug was stopped. Abdominal pain in patients on anticancer treatment is a common occurrence, but it is rarely investigated. Patients who receive ifosfamide as part of a chemotherapy regimen should be carefully monitored, and symptoms or signs suggestive of acute pancreatitis should be promptly investigated. Withholding the drug usually leads to complete recovery.
机译:已知用于治疗小儿实体瘤的异环磷酰胺具有严重的副作用,包括急性胰腺炎,这是一种罕见的治疗并发症。该报告描述了一个年轻女孩,该女孩在接受异环磷酰胺,卡铂和依托泊苷治疗的复发性Wilms肿瘤治疗中发展为急性胰腺炎。停药后不久,她完全康复,没有异环磷酰胺诱发的胰腺炎的后遗症。接受抗癌治疗的患者腹痛很常见,但很少进行研究。接受异环磷酰胺作为化疗方案一部分的患者应予以仔细监测,并应立即调查提示急性胰腺炎的症状或体征。停药通常会导致完全康复。

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