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首页> 外文期刊>Journal of Pediatric Surgery: Official Journal of the Surgical Section of the American Academy of Pediatric, the British Association of Paediatric Surgeons, the American Pediatric Surgical Association, and the Canadian Association of Paediatric Surgeons >D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics.
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D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics.

机译：短肠综合征中的D-乳酸酸中毒可通过抗生素和益生菌治疗。

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摘要

D-lactic acidosis sometimes occurs in malabsorbed patients with short-bowel syndrome and is characterized by recurrent episodes of encephalopathy and metabolic acidosis. The characteristic neurologic abnormalities and the presence of metabolic acidosis raises a diagnostic suspicion, and the diagnosis is made when the serum level of D-lactic acid is greater than 3 mmol/L. Standard treatment consists of restricting oral carbohydrates or fasting, correction of metabolic acidosis, and a long-term suppression of pathogenic floras with antibiotics. The authors present a case of D-lactic acidosis in a 22-year-old patient with short-bowel syndrome, to whom intestinal bacterial agents (probiotics) were given in addition to oral kanamycin. Recolonization of the intestine with nonpathogenic floras should be a long-term treatment for D-lactic acidosis.
机译：D-乳酸性酸中毒有时发生在吸收不良的短肠综合征患者中，其特征是脑病和代谢性酸中毒的反复发作。典型的神经系统异常和代谢性酸中毒的存在引起诊断怀疑，当D-乳酸的血清水平大于3 mmol / L时进行诊断。标准治疗包括限制口服碳水化合物或禁食，纠正代谢性酸中毒以及使用抗生素长期抑制病原菌。作者介绍了一个22岁的短肠综合征患者的D-乳酸酸中毒病例，除口服卡那霉素外，还给予了肠道细菌药物（益生菌）。肠道与非病原菌群的重新定殖应该是D-乳酸性酸中毒的长期治疗方法。

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