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首页> 外文期刊>Journal of Physics, D. Applied Physics: A Europhysics Journal >Removal of model proteins by means of low-pressure inductively coupled plasma discharge
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Removal of model proteins by means of low-pressure inductively coupled plasma discharge

机译:通过低压感应耦合等离子体放电去除模型蛋白

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摘要

Surgical instruments are intended to come into direct contact with the patients' tissues and thus interact with their first immune defence system. Therefore they have to be cleaned, sterilized and decontaminated, in order to prevent any kind of infections and inflammations or to exclude the possibility of transmission of diseases. From this perspective, the removal of protein residues from their surfaces constitutes new challenges, since certain proteins exhibit high resistance to commonly used sterilization and decontamination techniques and hence are difficult to remove without inducing major damages to the object treated. Therefore new approaches must be developed for that purpose and the application of non-equilibrium plasma discharges represents an interesting option. The possibility to effectively remove model proteins ( bovine serum albumin, lysozyme and ubiquitin) from surfaces of different materials ( Si wafer, glass, polystyrene and gold) by means of inductively coupled plasma discharges sustained in different argon containing mixtures is demonstrated and discussed in this paper.
机译:手术器械旨在与患者的组织直接接触,从而与患者的第一个免疫防御系统相互作用。因此,必须对它们进行清洁,消毒和去污,以防止任何类型的感染和炎症或排除疾病传播的可能性。从这个角度来看,从蛋白质表面去除蛋白质残留物构成了新的挑战,因为某些蛋白质对常用的灭菌和去污技术表现出很高的抵抗力,因此很难去除而不会对被处理物体造成重大损害。因此,必须为此目的开发新方法,并且非平衡等离子体放电的应用是一个有趣的选择。通过在不同的含氩混合物中维持的电感耦合等离子体放电,从不同材料(硅片,玻璃,聚苯乙烯和金)的表面有效去除模型蛋白(牛血清白蛋白,溶菌酶和泛素)的可能性已得到证明和讨论。纸。

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