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Immunoprophylactic activity of immunol, a polyherbal formulation against dexamethasone induced immunosuppression in rats

机译:免疫药(一种多草药制剂)对地塞米松诱导的大鼠免疫抑制的免疫预防活性

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摘要

The objective of this study was to evaluate the immunoprophylactic activity of immunol, a polyherbal formulation against dexamethasone induced immunosuppression in rats. The rats were administered oral doses of 1, 5 and 10 mL kg -1 b.wt., orally for 28 days following which immunosuppression was induced using dexamethasone (5 mg kg -1, twice daily for 3 days, intraperitoneally). Immunol at the dose of 10 mL kg -1 b.wt. exhibited prophylactic effect against dexamethasone induced immune suppression by way of both cell mediated and humoral mediated immunity.
机译:这项研究的目的是评估针对地塞米松诱导的大鼠免疫抑制作用的多草药制剂immunol的免疫预防活性。给大鼠口服1、5和10mL kg -1 b.wt.的口服剂量,持续28天,随后使用地塞米松(5mg kg -1,每天两次,共3天,腹膜内)诱导免疫抑制。剂量为10 mL kg -1 b.wt.通过细胞介导的和体液介导的免疫,均显示出对地塞米松诱导的免疫抑制的预防作用。

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