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首页> 外文期刊>Journal of pharmacology & toxicology. >Assessment of Thyroid Function in Male Workers of Battery Recycling Factory Occupationally Exposed to Lead
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Assessment of Thyroid Function in Male Workers of Battery Recycling Factory Occupationally Exposed to Lead

机译：铅暴露的电池回收厂男工人的甲状腺功能评估

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摘要

The association of long-term exposure to inorganic lead with harmful effects on thyroid function has not been well studied yet. The present cross-sectional study has investigated 195 male workers in a battery recycling factory in Iran. Thyroid function parameters were evaluated in relation to Blood Lead Level (BLL) and chelatable lead then compared in two subgroups of blood lead level based on Occupational Safety and Health Administration (OSHA) standards(<40 and >=40 mug dL~(-1)) and two subgroup of chelatable lead. Mean of BLL in study subjects was 43.44 mug dL~(-1) (14.2-85.6). No correlation between blood lead level and chelatable lead was found with thyroid indices. There was no statistically significant difference in thyroid indexes between workers with BLL<40 and workers with BLL >=40. Similarly, no statistically significant difference was seen in thyroid indices between workers with chelatable lead >=705 mug dL~(-1) and workers with chelatable lead >705 mug dL~(-1). No evidence of linear correlation between blood lead level, chelatable lead and thyroid function parameters was observed after adjustment for potential confounders (age, BMI, cigarette smoking, duration of exposure). In contrast to some studies with evidence of thyroid dysfunction in occupational lead exposure, this study showed no thyroid dysfunction in different levels of blood lead level up to 85 mug dL~(-1). .
机译：长期接触无机铅与对甲状腺功能有害影响的关系尚未得到很好的研究。本横断面研究调查了伊朗一家电池回收厂的195名男性工人。根据职业安全与卫生管理局（OSHA）标准（<40和> = 40马克杯dL〜（-1）评估与血铅水平（BLL）和可螯合铅有关的甲状腺功能参数，然后在两个血铅水平亚组中进行比较））和可螯合铅的两个子组。研究对象的BLL平均值为43.44马克杯dL〜（-1）（14.2-85.6）。血铅水平与可螯合铅之间的相关性与甲状腺指数无相关性。 BLL <40的工人和BLL> = 40的工人之间的甲状腺指数差异无统计学意义。同样，铅含量大于等于705 dL〜（-1）的螯合工人和铅含量大于705 dL〜（-1）的螯合工人的甲状腺指数在统计学上无显着差异。校正潜在混杂因素（年龄，BMI，吸烟，接触时间）后，未观察到血铅水平，可螯合的铅与甲状腺功能参数之间存在线性关系。与一些有证据表明在职业性铅暴露中甲状腺功能障碍的研究相反，该研究表明，在最高85 dL〜（-1）的不同血铅水平下，没有甲状腺功能障碍。 。

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