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首页> 外文期刊>Clinical hemorheology and microcirculation >Adverse effects of alcohol ingestion post exercise on blood rheological variables during recovery.
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Adverse effects of alcohol ingestion post exercise on blood rheological variables during recovery.

机译：运动后饮酒对康复期间血液流变学指标的不利影响。

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The present study examined the influence of ingesting a moderate dose of alcohol on the main determinants of blood rheology namely: plasma viscosity, plasma fibrinogen concentration, plasma total protein concentration, and haematocrit. Eleven moderately active young men were studied immediately after a standardised cycle ergometer test and during the 24 h period of recovery. Alcohol (0.7 g/kg body mass) was given 1 h after exercise on one test occasion, while an equal volume of alcohol-free solution was administered on the other. Venous blood samples were obtained at baseline, post exercise, and at 1, 5, and 22 h post alcohol ingestion. A significant reduction in plasma volume was observed immediately after exercise, but this decrease was restored 1-h post drink ingestion. Blood alcohol level increased significantly 1 h after the ingestion of alcohol, but decreased and returned to the resting baseline level at 5 h during recovery. Exercise induced significant changes (P<0.05) in blood rheology as manifested by a significant increase (P<0.05) in plasma viscosity and plasma fibrinogen. Parallel increase (P<0.05) in haematocrit and total protein was also observed after exercise. The increase in these rheological variables immediately after exercise was mainly due to exercise-induced plasma volume loss. During recovery, while the increase in haematocrit post-exercise returned to the baseline level in both control and alcohol trials, plasma viscosity and plasma fibrinogen remained significantly high during recovery in the alcohol trial compared with control condition. It is concluded that exercise induces significant changes in the main determinants of blood rheology and the consumption of alcohol after physical exercise delays the normal return of plasma viscosity, plasma fibrinogen to the resting baseline levels during recovery. Although the mechanism responsible for these findings is not, as yet known, it might be linked with alcohol induce dehydration.
机译：本研究检查了摄入适量酒精对血液流变学的主要决定因素的影响，这些因素包括：血浆粘度，血浆纤维蛋白原浓度，血浆总蛋白浓度和血细胞比容。在标准化的自行车测功机测试后以及恢复的24小时内，立即对11名中等活跃的年轻人进行了研究。一次运动后1小时给予酒精（0.7 g / kg体重），另一次给予等体积的无酒精溶液。在基线，运动后以及饮酒后1、5和22小时获取静脉血样。运动后立即观察到血浆量显着减少，但饮酒后1小时恢复了这种减少。摄入酒精后1小时，血液酒精水平显着上升，但在恢复期间5小时，血液酒精水平下降并恢复到静止的基线水平。运动引起血液流变学的显着变化（P <0.05），表现为血浆粘度和血浆纤维蛋白原的显着增加（P <0.05）。运动后还观察到血细胞比容和总蛋白平行增加（P <0.05）。运动后这些流变学变量的增加主要是由于运动引起的血浆容量减少。在恢复过程中，尽管对照和酒精试验中运动后的血细胞比容增加均恢复到基线水平，但酒精试验中恢复过程中的血浆粘度和血浆纤维蛋白原与对照组相比仍显着较高。结论是，运动引起血液流变学的主要决定因素发生显着变化，而运动后饮酒会延迟血浆粘度，血浆纤维蛋白原正常恢复到正常水平，从而延迟正常恢复。尽管尚不清楚导致这些发现的机制，但它可能与酒精引起的脱水有关。

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