...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of primary care & community health. >Treatment Outcomes Among People Living With HIV Who Are Food Insecure and Prescribed Antiretrovirals Taken With Food
【24h】

Treatment Outcomes Among People Living With HIV Who Are Food Insecure and Prescribed Antiretrovirals Taken With Food

机译：食物不安全和规定的食物抗逆转录病毒药物感染者中的治疗结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Food insecurity is a known barrier to medication adherence among people living with HIV. Antiretroviral therapies (ART) that require food likely pose added challenges to patients who do not have reliable access to food. This study examines the health implications of prescribing ART that requires food to patients who are food insecure. Method: A community sample of 538 men and 221 women currently taking ART to treat their HIV infection completed computerized interviews, biweekly unannounced pill count adherence assessments, and obtained their HIV RNA (viral load) and CD4 cell count from medical records. Results: Sixty-three percent of participants experienced at least I indicator of food insecurity during the previous month, of which 274 (57%) were prescribed an ART regimen that requires food. Among participants who were food insecure, individuals taking ART requiring food indicated significantly greater HIV symptoms, had lower CD4 cell counts, and poorer HIV suppression. For participants who were food secure, those taking ART that requires food were significantly less adherent than those whose ART regimen does not require food. Conclusions: People living with HIV who experience food insecurity are significantly more likely to be prescribed ART regimens that require food and experience poorer treatment outcomes. Determination of optimal ART regimens should take patient access to food into account and treatment guidelines should explicitly highlight the importance of food access in selecting ART regimens.
机译：背景：粮食不安全是艾滋病毒携带者中坚持药物治疗的已知障碍。需要食物的抗逆转录病毒疗法（ART）可能给无法可靠获取食物的患者带来更多挑战。这项研究检验了开处方抗病毒药物对健康不安全的患者的健康影响。方法：社区样本中目前正在接受抗病毒治疗的538名男性和221名女性进行了计算机访谈，每两周进行一次未宣布的药丸计数依从性评估，并从医疗记录中获得了其HIV RNA（病毒载量）和CD4细胞计数。结果：63％的参与者在上个月经历了至少I项粮食不安全指标，其中274名（57％）被处方了需要食物的抗逆转录病毒疗法。在食物不安全的参与者中，需要接受食物的抗逆转录病毒疗法的个体显示出明显更大的HIV症状，更低的CD4细胞计数和更弱的HIV抑制能力。对于那些有食品安全的参与者，那些需要抗病毒治疗的人比抗病毒治疗不需要食物的人的依从性要差得多。结论：经历食物不安全的HIV感染者更有可能被要求接受食物且治疗效果较差的抗逆转录病毒疗法。确定最佳抗病毒治疗方案时应考虑患者获得食物的可能性，治疗指南应明确强调选择抗病毒治疗方案中获得食物的重要性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号