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CT- and computer-based features of small hamartomas.

机译:小型错构瘤的CT和基于计算机的特征。

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PURPOSE: To identify characteristic computed tomographic (CT) and computer-derived features of hamartomas manifesting as small pulmonary nodules. METHODS: Individuals with a diagnosis of hamartoma were identified among participants in the International Early Lung Cancer Action Program and were included if there thin section CT images that included the entire nodule. The CT findings were reviewed to determine the nodule consistency (solid, part-solid, nonsolid), nodule diameter (average of length and width), shape (round, lobulated, neither) and edge (smooth, not smooth). Computer measures of nodule compactness, sphericity, surface regularity and gradient (change in gray-scale between the nodule and the surrounding parenchyma) were determined. Volume doubling time (VDT) was also determined for those with at least two scans with similar imaging acquisitions. RESULTS: A total of 21 cases of hamartomas that had histologic or cytologic confirmation were identified. The median age was 60 and 12 (57%) were men. Average diameter was 10.7 mm (5-20.7 mm). All were solid in consistency and were described by the radiologist as having either round or lobulated shape with a smooth edge. None had pathognomonic radiologic findings for hamartoma. Computer measures demonstrated that all were compact and spherical, with a regular surface and a sharp margin between the nodule and surrounding parenchyma. Of nine on whom the VDT could be calculated, eight had VDTs longer than 450 days. CONCLUSION: Both radiologist and computer derived features of small hamartomas suggest a consistent presentation for these lesions which may be helpful in distinguishing them from other types of nodules.
机译:目的:鉴定表现为小肺结节的错构瘤的特征性计算机断层扫描(CT)和计算机衍生特征。方法:在国际早期肺癌行动计划的参与者中鉴定出患有错构瘤的个体,如果薄层CT图像包括整个结节,则将其包括在内。检查CT结果以确定结节的稠度(实心,部分实心,非实心),结节直径(长度和宽度的平均值),形状(圆形,小叶形,均非)和边缘(光滑,不光滑)。确定了结节紧密度,球形度,表面规则性和梯度(结节与周围薄壁组织之间的灰度变化)的计算机测量值。还为至少两次扫描且成像相似的患者确定了体积加倍时间(VDT)。结果:总共鉴定出21例经组织学或细胞学证实的错构瘤病例。中位年龄为60岁,男性为12岁(57%)。平均直径为10.7毫米(5-20​​.7毫米)。所有这些都具有坚固的一致性,并且放射科医生将其描述为具有光滑边缘的圆形或小叶形状。没有人发现错构瘤的影像学影像学表现。计算机测量表明,它们都是致密的球形,表面规则,结节与周围实质之间有尖锐的边缘。在可以计算VDT的9个中,有8个的VDT超过450天。结论:放射影像学和计算机衍生的小错构瘤特征均提示这些病变一致,这可能有助于将其与其他类型的结节区分开。

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