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首页> 外文期刊>Clinical imaging >Suspiciously malignant findings on ultrasound after fine needle aspiration biopsy in a thyroid nodule with initially benign ultrasound and cytologic result: To repeat or to follow-up
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Suspiciously malignant findings on ultrasound after fine needle aspiration biopsy in a thyroid nodule with initially benign ultrasound and cytologic result: To repeat or to follow-up

机译：甲状腺结节细针穿刺活检后超声检查可疑恶变，初步超声检查和细胞学检查结果为良性：重复或随访

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摘要

Purpose: The purposes of this study were to evaluate the incidence of suspiciously malignant change on ultrasound (US) in thyroid nodules after initial benign US and cytologic results and to investigate the associated US characteristics and the management of these nodules. Materials and methods: Among the patients who underwent thyroid fine needle aspiration biopsy (FNAB) from October 2003 to December 2004, 550 patients who had thyroid nodules with initial benign US and cytologic results were included. Reference standards were established by pathologic results, follow-up cytologic results or follow-up US. We evaluated the incidence of morphologic changes to suspiciously malignant US findings of these thyroid nodules after FNAB. We also evaluated the initial US features associated with the nodules showing suspiciously malignant findings on US after FNAB in these patients. Results: Of 550 patients, 28 nodules (5.1%) showed morphologic changes into nodules with suspiciously malignant US findings on follow-up US. All thyroid nodules showing morphologic changes had mixed solid and cystic components (P<.001). Suspiciously malignant changes on US were associated with the percentage of the cystic portion, but all changed nodules were confirmed as benign. Conclusion: Follow-up US should be recommended rather than to repeat FNAB for thyroid nodules with initial benign US and cytologic results even if they later develop suspiciously malignant US features after FNAB.
机译：目的：本研究的目的是评估在最初的良性US和细胞学检查结果后甲状腺结节中超声（US）可疑恶变的发生率，并调查相关的US特征和这些结节的管理。材料和方法：在2003年10月至2004年12月进行甲状腺细针穿刺活检（FNAB）的患者中，包括550例甲状腺结节的患者，这些患者最初具有良好的US和细胞学检查结果。通过病理结果，后续细胞学结果或后续US建立参考标准。我们评估了FNAB后这些甲状腺结节的可疑恶性美国发现的形态学改变的发生率。我们还评估了与这些结节相关的初始US特征，这些患者在FNAB后显示出可疑的恶性超声表现。结果：在550例患者中，有28个结节（5.1％）显示形态学改变为结节，在随访US时发现其可疑恶性。所有表现出形态学变化的甲状腺结节都有混合的固体和囊性成分（P <.001）。在US上可疑的恶性变化与囊性部分的百分比有关，但所有结节改变均被确认为良性。结论：应该建议随访US，而不是对最初具有良性US和细胞学结果的甲状腺结节重复FNAB，即使它们后来在FNAB之后发展为可疑的恶性美国特征。

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