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首页> 外文期刊>Journal of psychosomatic research >Predictors of treatment outcome after cognitive behavior therapy and antispasmodic treatment for patients with irritable bowel syndrome in primary care.
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Predictors of treatment outcome after cognitive behavior therapy and antispasmodic treatment for patients with irritable bowel syndrome in primary care.

机译：初级保健中肠易激综合征的认知行为治疗和痉挛治疗后治疗结果的预测指标。

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OBJECTIVE: To examine predictors of treatment outcome in IBS-patients who participated in a randomized controlled trial in primary care, where 149 irritable bowel syndrome (IBS) patients were randomized to mebeverine hydrochloride (n=77) or mebeverine+cognitive behavior therapy (CBT) (n=72). CBT offered additional benefit over mebeverine alone. METHODS: Regression analyses were used to identify predictors of work and social adjustment 12 months after treatment ended. The intervention groups were analyzed separately in order to look at the separate effects in each group. RESULTS: Lower levels of psychological distress (anxiety and depression) at baseline predicted a good outcome in the mebeverine group [beta=0.388 (95% CI: 0.065-0.936), P=.025] but not in the mebeverine+CBT group. In the adjusted model for the mebeverine+CBT group less adaptive IBS related behavioral coping predicted a good outcome [beta=0.285 (95% CI: 0.002-0.210), P=.045]. CONCLUSION: Different factors are associated with outcome depending on the treatment received. At assessment clinicians should assess patients coping styles and may want to consider recommending CBT to those patients with IBS in primary care who are engaging in unhelpful coping behavior.
机译：目的：研究参加初级保健随机对照试验的IBS患者的治疗结果的预测因素，其中149名肠易激综合征（IBS）患者被随机分配接受盐酸美贝维林（n = 77）或美贝维林+认知行为疗法（CBT） ）（n = 72）。与仅美贝维林相比，CBT提供了更多好处。方法：回归分析用于确定治疗结束后12个月工作和社会适应的预测指标。干预组分别进行了分析，以查看每组中的单独作用。结果：基线时较低的心理困扰（焦虑和抑郁）水平预示着美贝维林组的良好结局[β= 0.388（95％CI：0.065-0.936），P = .025]，但美贝维林+ CBT组则没有。在美贝维林+ CBT组的调整模型中，较少的适应性IBS相关行为应对预测了良好的预后[β= 0.285（95％CI：0.002-0.210），P = .045]。结论：取决于所接受的治疗，不同的因素与预后相关。在评估时，临床医生应评估患者的应对方式，并可能要考虑向从事无助应对行为的初级保健IBS患者推荐CBT。

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