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Therapeutic strategies in multiple sclerosis

机译:多发性硬化症的治疗策略

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摘要

Treatment options for multiple sclerosis (MS) have significantly expanded over the past decade, and evolved from a relatively restricted choice of disease modifying therapies of interferon-beta and glatiramer acetate, to the current situation characterized by the availability of a wide range of different oral therapies and monoclonal antibodies to treat MS patients. This new treatment era in MS certainly poses an exciting challenge for neurologists to decide on the best therapeutic option for each particular patient at a given time. In this context, an in-depth knowledge of the mechanisms of action of the new MS therapeutic strategies and the potential adverse effects associated with them will help in the assessment of the benefits and risks of each particular treatment and contribute to the treatment decision-making process.
机译:在过去的十年中,多发性硬化症(MS)的治疗选择已大大扩展,并从相对有限的疾病改良疗法(干扰素-β和醋酸格拉替雷)的选择演变为以多种口服药物的可用性为特征的当前状况。治疗和MS患者的单克隆抗体。 MS的这个新的治疗时代无疑给神经科医师提出了一个激动人心的挑战,那就是在给定的时间为每个特定患者决定最佳的治疗选择。在这种情况下,对新的MS治疗策略的作用机理及其潜在的不良影响的深入了解将有助于评估每种特定治疗的益处和风险,并有助于治疗决策处理。

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