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首页> 外文期刊>Clinical immunology: The official journal of the Clinical Immunology Society >The CCR5 delta 32 polymorphism (rs333) is not associated with Sj?gren's syndrome or Type 1 Diabetes in Colombians
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The CCR5 delta 32 polymorphism (rs333) is not associated with Sj?gren's syndrome or Type 1 Diabetes in Colombians

机译：CCR5 delta 32多态性（rs333）与Sj？gren综合征或哥伦比亚人1型糖尿病无关

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Objective: This study aims to examine the associations between asthma, secondhand smoke exposure and healthcare utilization in a nationally representative sample of children. Methods: Data from 5686 children aged 0-11. years were analyzed. Healthcare utilization, asthma diagnosis and demographic information came from the 2001 and 2006 Medical Expenditure Panel Surveys. Secondhand smoke exposure was measured during the 2000 and 2005 National Health Interview Surveys. Multivariable regression models were used to determine the association between secondhand smoke exposure, asthma diagnosis and healthcare utilization (hospitalizations, emergency department visits, outpatient visits and prescription medication use). Results: Asthma modified the relationship between secondhand smoke exposure and hospitalizations, as exposure more than doubled the odds of hospitalization among children with asthma but had no effect on children without asthma. Secondhand smoke exposure increased the odds by 37% of emergency room visits (P < 0.001), but was not associated with outpatient visits or medication use. Children with asthma had a higher odds of utilizing all healthcare services (P < 0.001). Conclusions: Secondhand smoke exposure was associated with a greater utilization of hospitals and emergency departments, and the effect on hospitalizations was most pronounced among children with asthma. Reducing secondhand smoke exposure would help to reduce the burden on the healthcare system, especially among children with asthma.
机译：目的：本研究旨在探讨全国代表性儿童样本中哮喘，二手烟暴露与医疗保健利用之间的关系。方法：来自5686位0-11岁儿童的数据。年进行了分析。医疗保健利用率，哮喘诊断和人口统计学信息来自2001年和2006年医疗支出小组调查。在2000年和2005年的国家健康访问调查中测量了二手烟暴露量。使用多变量回归模型确定二手烟暴露，哮喘诊断与医疗保健利用之间的关联（住院，急诊就诊，门诊就诊和处方药使用）。结果：哮喘改变了二手烟暴露与住院之间的关系，因为哮喘患儿接触二手烟的几率翻了一番以上，但对没有哮喘的孩子没有影响。二手烟暴露使急诊就诊的几率增加了37％（P <0.001），但与门诊就诊或药物使用无关。哮喘患儿使用所有医疗服务的可能性更高（P <0.001）。结论：二手烟暴露与医院和急诊部门的更多利用有关，哮喘患儿对住院的影响最为明显。减少二手烟接触量将有助于减轻医疗保健系统的负担，尤其是在哮喘患儿中。

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