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首页> 外文期刊>Journal of psychiatric research >Depression, anxiety and cognition in community-dwelling adults aged 70 years and over
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Depression, anxiety and cognition in community-dwelling adults aged 70 years and over

机译：70岁及以上社区居民的抑郁，焦虑和认知

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Although there is evidence of associations between anxiety, depression and cognitive function in old age, there is little work investigating relations between those variables over an extended period of time. Therefore, we used data from the Canberra Longitudinal Study to investigate 12-year cognitive change over four measurement points in relation to anxiety and depression symptoms. Latent growth models on over 836 community-dwelling persons aged 70 years and over, recruited from the electoral roll suggested that higher depression symptom scores were associated with poorer initial performance in processing speed, verbal fluency and episodic memory while higher anxiety symptom scores were associated with verbal fluency. We found no evidence that mental health variables affected change in cognition over time. Importantly, when possible mild cognitive impairment or dementia cases were removed from the models, associations between the cognitive variables and depression symptoms disappeared while those for anxiety symptoms strengthened. The findings are consistent with the possibility that depression-related cognitive deficits represent a prodrome or risk factor for dementia while associations between anxiety and cognition may be more characteristic of normal aging.
机译：尽管有证据表明，老年人的焦虑，抑郁和认知功能之间存在关联，但很少有研究工作可以长期研究这些变量之间的关系。因此，我们使用了来自堪培拉纵向研究的数据来调查与焦虑和抑郁症状有关的四个测量点的12年认知变化。从选民名册中收集的超过836名70岁及以上的社区居民的潜在增长模型表明，抑郁症状评分较高与处理速度，口语流利性和情景记忆的初期表现较差有关，而焦虑症状评分与较高的焦虑表现有关。语言流利。我们没有发现证据表明心理健康变量会影响认知随时间的变化。重要的是，当从模型中删除可能的轻度认知障碍或痴呆病例时，认知变量和抑郁症状之间的关联会消失，而焦虑症状的认知变量和关联会增强。该发现与抑郁相关的认知缺陷代表痴呆症的前兆或危险因素，而焦虑与认知之间的关联可能是正常衰老的特征相一致。

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