Natural killer cells in human health and disease.

Orange JS; Ballas ZK

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Natural killer cells in human health and disease.

机译：天然杀伤细胞在人类健康和疾病中。

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Natural killer (NK) cells are lymphocytes of the innate immune system that are critical in host defense and immune regulation. They are activated or inhibited through the ligation of germline-encoded receptors and are involved in mediating cytotoxicity, in producing cytokines and in providing co-stimulation to cells of the adaptive immune system. NK cells play important roles in viral infections, autoimmunity, pregnancy, cancer and bone marrow transplantation. This review highlights recent developments in the understanding of the role of human NK cells in health and disease.

机译：天然杀伤（NK）细胞是先天免疫系统的淋巴细胞，对宿主防御和免疫调节至关重要。它们通过种系编码受体的连接而被激活或抑制，并参与介导细胞毒性，产生细胞因子并向适应性免疫系统的细胞提供共刺激。 NK细胞在病毒感染，自身免疫，妊娠，癌症和骨髓移植中起重要作用。这篇综述强调了对人类NK细胞在健康和疾病中作用的理解的最新进展。

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《Clinical immunology: The official journal of the Clinical Immunology Society》 |2006年第1期|共10页
作者
Orange JS; Ballas ZK;
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正文语种 eng
中图分类临床医学;
关键词
Disease; Health; Killer Cells; Natural; 疾病; 卫生; 杀伤细胞; 天然;

机译：Disease;Health;Killer Cells;Natural;疾病;卫生;杀伤细胞;天然;

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专利

1. Human natural killer cells in health and disease. [J] . Shereck E, Satwani P, Morris E, Pediatric blood & cancer . 2007,第5期

机译：人类天然杀伤细胞在健康和疾病中的作用。
2. Role of human natural killer cells in health and disease. [J] . T L Whiteside, R B Herberman Clinical and diagnostic laboratory immunology . 1994,第2期

机译：人类自然杀伤细胞在健康和疾病中的作用。
3. Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease. [J] . Boyton RJ, Altmann DM Clinical and Experimental Immunology: An Official Journal of the British Society for Immunology . 2007,第1期

机译：疾病中的天然杀伤细胞，杀伤性免疫球蛋白样受体和人类白细胞抗原I类。
4. GENERATION OF NATURAL KILLER CELLS FROM SERUM-FREE EXPANDED CD34~+ CELLS ISOLATED FROM HUMAN UMBILICAL CORD BLOOD [C] . I-Ting Kao, Zwe-Ling Kong, Mei-Ling Wu, Annual Meeting of the Japanese Association for Animal Cell Technology . 2006

机译：从无血清膨胀的CD34〜+细胞中产生自然杀伤细胞的产生从人脐带血中分离的细胞
5. Epigenetic regulation of killer immunoglobulin-like receptor gene expression in developing human natural killer cells. [D] . Cichocki, Frank M. 2010

机译：发育中的人类自然杀伤细胞中杀伤免疫球蛋白样受体基因表达的表观遗传调控。
6. Role of human natural killer cells in health and disease. [O] . T L Whiteside, R B Herberman 1994

机译：人类自然杀伤细胞在健康和疾病中的作用。
7. Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11 [O] . Montoya, Carlos J, Pollard, David, Martinson, Jeffrey, 2007

机译：使用新型不变性自然杀伤T细胞克隆型单克隆抗体6B11表征健康和疾病中人类不变性自然杀伤T亚群
8. Persistently Low Natural Killer Cell Activity and Circulating Levels of Plasma Beta Endorphin: Risk Factors for Infectious Disease. [R] . Levy, S. M., Fernstrom, J., Herberman, R. B., 1990

机译：持续低自然杀伤细胞活性和血浆β内啡肽的循环水平：传染病的危险因素。

Natural killer cells in human health and disease.

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