On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers

Agnati L.F.; Guidolin D.; Vilardaga J.P.; Ciruela F.; Fuxe K.

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On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers

机译：关于GPCR领域中不断扩展的术语：受体镶嵌和受体异聚体的含义

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The oligomerization of G protein-coupled receptors (GPCRs) is a fact that deserves further attention as increases both the complexity and diversity of the receptor-mediated signal transduction, thus enriching the cell signaling. Consequently, in the present review we tackle among others the problems concerning the terminology used to describe aspects surrounding the GPCRs oligomerization phenomenon. Therefore, the theoretical implications of the GPCR oligomerization will be briefly discussed together with possible implications of this phenomenon especially for new strategies in drug development.

机译：G蛋白偶联受体（GPCR）的寡聚化是一个事实，由于增加了受体介导的信号转导的复杂性和多样性，从而丰富了细胞信号，因此值得进一步关注。因此，在本综述中，我们将解决与用于描述GPCR低聚现象相关方面的术语有关的问题。因此，将简要讨论GPCR寡聚化的理论意义以及该现象的可能意义，尤其是对于药物开发的新策略。

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《Journal of receptor and signal transduction research》 |2010年第5期|共17页
作者
Agnati L.F.; Guidolin D.; Vilardaga J.P.; Ciruela F.; Fuxe K.;
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正文语种 eng
中图分类细胞形态学;
关键词
Oligomerization; Receptorreceptor interactions; Spatial arrangement; Stoichiometry;

机译：齐聚;受体-受体相互作用;空间排列;化学计量;

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1. On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers [J] . Agnati L.F., Guidolin D., Vilardaga J.P., Journal of receptor and signal transduction research . 2010,第5期

机译：关于GPCR领域中不断扩展的术语：受体镶嵌和受体异聚体的含义
2. G Protein-Coupled Receptor Heteromer Identification Technology: Identification and Profiling of GPCR Heteromers [J] . Sanam Mustafa, Kevin D.G. Pfleger Journal of Laboratory Automation . 2011,第4期

机译：G蛋白偶联受体异构体鉴定技术：GPCR异构体的鉴定和分析
3. G Protein-Coupled Receptor Heteromer Identification Technology: Identification and Profiling of GPCR Heteromers [J] . Sanam Mustafa, Kevin D.G. Pfleger SLAS Technology . 2011,第4期

机译：G蛋白偶联受体异构体鉴定技术：GPCR异构体的鉴定和分析
4. Coordination chemogenetics for allosteric activation of endogenous GPCR-type glutamate receptors [C] . Kento Ojima, Wataru Kakegawa, Yukiko Michibata 日本化学会春季年会講演予稿集 . 2018

机译：内源性GPCR型谷氨酸受体构想激活的协调化学物质
5. The Modulatory Role of Caffeine and Other Adenosine Receptor Antagonists onto Spinal Locomotor Circuits: Evidence for its Dependence on Adenosine A1- Dopamine D1 Receptor Heteromers in Spinal Motoneurons. [D] . Rivera-Oliver, Marla. 2017

机译：咖啡因和其他腺苷受体拮抗剂对脊髓运动回路的调节作用：证据表明其依赖于脊髓Motonuron中的腺苷A1-多巴胺D1受体异源异构体。
6. On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers [O] . Luigi F. Agnati, Diego Guidolin, Jean Pierre Vilardaga, -1

机译：关于GPCR场的扩展术语：受体马赛克与受体异构体的含义
7. On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers [O] . Agnati LF, D. GUIDOLIN, Vilardaga JP, 2010

机译：关于GPCR领域中不断扩展的术语：受体镶嵌和受体异聚体的含义

On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers

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