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首页> 外文期刊>Journal of Reproductive Medicine: The Official Periodical of the American Academy of Reproductive Medicine, Association of Professors of Gynecology and Obstetrics, International Family Planning Research Association ... [et al.] >Abruptio placentae associated with misoprostol use in women with preeclampsia.
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Abruptio placentae associated with misoprostol use in women with preeclampsia.

机译：子痫前期妇女使用米索前列醇引起的胎盘早破。

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OBJECTIVE: To evaluate complications associated with cervical ripening with vaginal administration of misoprostol and dinoprostone vaginal inserts in women with preeclampsia. preeclampsia. STUDY DESIGN: Retrospective study of patients with preeclampsia undergoing cervical ripening with vaginal misoprostol and dinoprostone vaginal inserts prior to labor induction. RESULTS: Among 203 patients with preeclampsia undergoing cervical ripening prior to induction, 95 received vaginal misoprostol, and 108 received dinoprostone. The incidence of uterine hyperstimulation requiring medical therapy and the need for emergency cesarean section due tofetal heart rate abnormalities were significantly higher among patients receiving misoprostol (22.1% versus 12.0%, p = 0.04, and 17.9% versus 8.3%, p = 0.03, respectively). The overall incidence of abruptio placentae was 7.4%, with a significantly higher incidence among those receiving misoprostol as compared to dinoprostone (13.7% versus 1.9%, p = 0.001). CONCLUSION: Among patients with preeclampsia undergoing cervical ripening prior to labor induction, there is a higher incidence of acute intrapartum complications (uterine hyperstimulation, cesarean section for fetal heart rate abnormalities and abruptio placentae) with vaginal misoprostol, as compared to dinoprostone, vaginal insert.
机译：目的：评估子痫前期妇女阴道给予米索前列醇和地诺前列酮阴道插入物与宫颈成熟相关的并发症。子痫前期。研究设计：回顾性研究先兆子痫患者，在接受引产前先用阴道米索前列醇和地诺前列酮阴道插片进行宫颈成熟。结果：203例先兆子痫患者在诱导前先进行宫颈成熟，其中95例接受阴道米索前列醇，108例接受狄诺前列酮。接受米索前列醇的患者中需要药物治疗的子宫过度刺激的发生率和因胎儿心率异常而需要紧急剖宫产的发生率显着更高（分别为22.1％对12.0％，p = 0.04，17.9％对8.3％，p = 0.03 ）。胎盘早破的总发生率为7.4％，与米诺前列酮相比，米索前列醇的发生率显着更高（13.7％对1.9％，p = 0.001）。结论：先兆子痫患者在引产前先进行子宫颈成熟，与米诺前列酮，阴道插入物相比，阴道米索前列醇的急性分娩并发症（子宫过度刺激，剖宫产胎儿心率异常和胎盘早剥）的发生率更高。

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