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首页> 外文期刊>Journal of Reproductive Medicine: The Official Periodical of the American Academy of Reproductive Medicine, Association of Professors of Gynecology and Obstetrics, International Family Planning Research Association ... [et al.] >Twin mole and viable fetus: The case for misdiagnosis.
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Twin mole and viable fetus: The case for misdiagnosis.

机译：双胎和活胎儿：误诊的情况。

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摘要

OBJECTIVE: To report the Sheffield Trophoblast Centre experience of twin molar gestations and review this in the light of international experience. CASE: Thirty patients with possible twin molar gestations were registered from 1986 to 2004 (during which period 7,200 cases of mole were seen). The accuracy of suspected clinical and histologic diagnoses was investigated. RESULTS: In 10 cases twin mole/fetus had been suspected clinically but not confirmed when products of conception were examined. In 3 of these cases the pregnancy had been therapeutically terminated because of clinical (ultrasound) suspicion of coexisting molar pregnancy. In the 19 cases where twin mole/fetus was suspected, central histopathology review was possible in 14 cases. Only 7 were confirmed. In 2 further cases twin molar gestation was diagnosed on specimens referred for central review as partial mole singleton pregnancies. For confirmed cases the pregnancy outcome was term delivery in 5 cases and miscarriage in 4. CONCLUSION: Clinical and histopathologic diagnosis of twin molar pregnancies is inaccurate in many suspected cases; therefore, a second (expert) opinion should be sought. When the diagnosis is accurate, maternal and fetal complications are common. However, in suspected cases the pregnancy may be allowed to proceed, with caution, if the mother wishes.
机译：目的：报告谢菲尔德滋养细胞中心双胎磨牙妊娠的经验，并根据国际经验对此进行回顾。案例：1986年至2004年，共登记了30例可能患有双胎磨牙的患者（在此期间共观察到7200例葡萄胎）。调查怀疑的临床和组织学诊断的准确性。结果：10例双胎痣/胎儿在临床上被怀疑，但在检查受孕产物时未得到证实。在这些案例中的3例中，由于临床（超声）怀疑并存磨牙妊娠而终止了治疗。在怀疑双胎痣/胎儿的19例中，有14例可以进行中央组织病理学复查。仅确认了7个。在另外2例病例中，被诊断为双侧磨牙妊娠的标本被诊断为部分性单胎妊娠。对于确诊的病例，妊娠结局为5例足月分娩，4例为流产。结论：在许多疑似病例中，双胎磨牙的临床和组织病理学诊断均不准确。因此，应该寻求第二（专家）意见。诊断准确后，母婴合并症很常见。但是，在怀疑的情况下，如果母亲愿意的话，可以允许怀孕谨慎进行。

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