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首页> 外文期刊>Journal of refractive surgery >One-year outcomes of epi-LASIK for myopia.
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One-year outcomes of epi-LASIK for myopia.

机译：Epi-LASIK治疗近视的一年结局。

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PURPOSE: To evaluate the early clinical outcomes of epi-LASIK for myopia. METHODS: This study comprised 302 eyes of 162 patients. Epi-LASIK was performed with an automatically rotational epikeratome (KM-5000D). Epithelial separation was achieved mechanically without the use of alcohol. After laser ablation, the epithelial sheet was repositioned and a therapeutic contact lens was applied to the cornea immediately for 3 to 5 days. Postoperative visual acuity, symptoms, epithelial sheet, contrast sensitivity, wavefront aberration, and haze formation were evaluated 3, 6, and 12 months postoperatively. RESULTS: Of the 302 eyes, 72 eyes (42 patients) with a mean spherical equivalent refraction of -9.13 +/- 4.23 diopters (D) (range: -1.25 to -19.0 D) had > 1-year follow-up. One eye failed to make the epithelial sheet because of the narrow palpebral fissure. An integrated epithelial sheet with a diameter of 8 to 9 mm was made in 289 (95.7%) eyes, leaving a superior hinge of approximately 2 to 4 mm. In 1 eye, stromal tissue remained in the epithelial sheet. Free epithelial flaps were made in 12 (4%) eyes. Mild discomfort was reported by 150 patients (282 eyes, 93.4%). Twelve patients (20 eyes, 6.6%) reported moderate symptoms. At 1 day postoperatively, corneal epithelium was almost transparent or had mild focal edema in 288 (95.4%) eyes; moderate edema was reported in 14 (4.6%) eyes. At 1 year postoperatively, spherical equivalent refraction of 60 (83.3%) eyes was within +/- 1.0 D of attempted refraction. Grade 0.5 haze was found in 2 eyes; all other eyes had no haze. No eye lost any lines of best spectacle-corrected visual acuity (BSCVA), whereas 12 (16.7%) of 72 eyes gained one or two lines of BSCVA. Contrast sensitivity decreased 1 month postoperatively and was restored to preoperative levels in eyes with preoperative spherical equivalent refraction < -10.0 D. Higher order aberration increased significantly postoperatively. CONCLUSIONS: Epi-LASIK is a safe and efficient method to correct myopia with the advantage that it has only mild symptoms and mild haze. A larger study with longer follow-up is needed to determine its long-term clinical outcomes.
机译：目的：评估epi-LASIK治疗近视的早期临床疗效。方法：该研究包括162例患者的302只眼。 Epi-LASIK用自动旋转的表皮角膜刀（KM-5000D）进行。机械上皮分离是在不使用酒精的情况下完成的。激光消融后，将上皮片重新放置，然后将治疗性隐形眼镜立即施用于角膜3至5天。术后3、6和12个月评估术后视力，症状，上皮片，对比敏感度，波前像差和雾度形成。结果：在302眼中，有72眼（42例患者）的平均球面等效屈光度为-9.13 +/- 4.23屈光度（D）（范围：-1.25至-19.0 D），随访时间> 1年。一只眼睛由于睑裂狭窄而无法上皮。在289只（95.7％）眼中制成直径8至9毫米的完整上皮薄片，留下约2至4毫米的上铰链。在1只眼中，基质组织保留在上皮片中。在12只（4％）眼中制作了游离的上皮瓣。 150名患者报告了轻度不适感（282眼，93.4％）。 12名患者（20眼，6.6％）报告有中度症状。术后1天，288只（95.4％）眼睛的角膜上皮几乎透明或有轻度局灶性水肿。据报道有14只（4.6％）眼出现中度浮肿。术后1年，60眼（83.3％）的等效球镜屈光度在尝试屈光度的+/- 1.0 D之内。在2只眼睛中发现0.5级雾度;其他所有的眼睛都没有雾霾。没有一只眼睛丧失任何获得最佳眼镜矫正视力（BSCVA）的视力，而72眼中有12眼（16.7％）获得了一到两行BSCVA。术后1个月，对比敏感度降低，眼球等效屈光度<-10.0 D的眼睛恢复到术前水平。术后高阶像差显着增加。结论：Epi-LASIK矫正近视是一种安全有效的方法，其优点是仅具有轻度的症状和轻度的雾霾。需要进行更大范围的随访，以便确定其长期临床结果。

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