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首页> 外文期刊>Journal of postgraduate medicine >Family burden, quality of life and disability in obsessive compulsive disorder: An Indian perspective.
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Family burden, quality of life and disability in obsessive compulsive disorder: An Indian perspective.

机译：强迫症的家庭负担，生活质量和残疾：印度的观点。

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Background: Obsessive compulsive disorder (OCD) is a psychiatric disorder that often tends to run a chronic course. The lifetime prevalence of OCD is around 1-3%, which is twice as prevalent as schizophrenia and bipolar disorder. Aim: To asses the family burden, quality of life (QoL) and disability in patients suffering from at least moderately ill OCD and then to compare them with schizophrenia patients of comparable severity. Settings and Design: We recruited 70 consecutive subjects (OCD=35, schizophrenia=35) who met study criteria between March 2005 and March 2006 from the psychiatric services of the National Institute of Mental Health and Neuro Sciences, Bangalore, India. Materials and Methods: The severity of illness was rated using the Clinical Global Impression-Severity (CGI-S). Instruments used in the current study were the Family Burden Schedule, the World Health Organization (WHO) QoL (Bref) and the WHO - Disability Assessment Schedule (DAS). Statistical Analysis: The Fisher's exact test/chi-square test was used to compare categorical variables and the independent sample t test was used to analyze continuous variables. Analysis of covariance (ANCOVA) was used to compare the groups after controlling for potential confounding variables. Pearson's correlation was used for correlation analysis. Results: Overall family burden, financial burden and disruption of family routines were significantly higher in schizophrenia patients compared to OCD although the groups did not differ with respect to other domains of family burden. On the WHO QoL, OCD patients were comparable to schizophrenia patients with respect to the psychological and social domains. On the WHO - DAS, both the groups were similar in all the domains except getting around. Conclusion: Severe OCD is associated with significant disability, poor QoL and high family burden, often comparable to schizophrenia. Therefore, there is an urgent need to increase the sensitivity among healthcare professionals to recognize and treat OCD.
机译：背景：强迫症（OCD）是一种精神病，通常倾向于慢性病。强迫症的终生患病率约为1-3％，是精神分裂症和躁郁症的两倍。目的：评估至少患有中度疾病的强迫症患者的家庭负担，生活质量（QoL）和残疾，然后将其与严重程度相当的精神分裂症患者进行比较。设置与设计：我们从印度班加罗尔国家心理健康与神经科学研究所的精神科服务中心招募了70位连续受试者（OCD = 35，精神分裂症= 35），这些受试者在2005年3月至2006年3月期间符合研究标准。材料和方法：使用临床总体印象严重度（CGI-S）对疾病的严重程度进行评分。当前研究中使用的工具是家庭负担表，世界卫生组织（WHO）的生活质量（Bref）和WHO-残疾评估表（DAS）。统计分析：Fisher精确检验/卡方检验用于比较分类变量，独立样本t检验用于分析连续变量。在控制潜在的混杂变量之后，使用协方差分析（ANCOVA）比较各组。皮尔逊相关性用于相关性分析。结果：与强迫症相比，精神分裂症患者的总体家庭负担，经济负担和家庭常规的破坏要高得多，尽管各组在其他家庭负担方面没有差异。在WHO QoL方面，就心理和社会领域而言，强迫症患者与精神分裂症患者相当。在WHO-DAS上，除了四处走动外，两组在所有领域都相似。结论：重度强迫症与严重残疾，生活质量较差和家庭负担高有关，通常可与精神分裂症相提并论。因此，迫切需要提高医疗保健专业人员识别和治疗强迫症的敏感性。

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