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首页> 外文期刊>Journal of shoulder and elbow surgery >Incidence and risk factors for acute infection after proximal humeral fractures: A multicenter study
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Incidence and risk factors for acute infection after proximal humeral fractures: A multicenter study

机译：肱骨近端骨折后急性感染的发生率和危险因素：多中心研究

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Background: The rate of acute infection after surgery for proximal humeral fractures is not known. The aims of this study were to report the incidence and to analyze the risk factors for infection after proximal humeral fracture treatment. Materials and methods: We report a retrospective multicenter study of 452 proximal humeral fractures. Data were modeled by use of univariate and/or linear regression analyses to determine the odds ratio (OR). A logistic regression analysis was used to check for demographic and other characteristics with the potential to confound a true association between risk factors and infection. Results: The mean age was 62.1 years, and 314 patients were female patients. Of the patients, 18 (4%) had an acute infection. The factors that correlated with infection were length of surgery (OR, 1.009; P = .05), preoperative skin preparation with chlorhexidine gluconate (OR, 0.13; P = .008), and prophylactic antibiotic (OR, 10.73; P = .03). The delay to surgery was close to achieving significance (OR, 1.71; P = .06). Conclusion: This study suggests that washing the shoulder with chlorhexidine gluconate and avoiding the use of first-generation cephalosporin in favor of more effective prophylactic therapy are effective at reducing the risk of infection after treatment for proximal humeral fractures.
机译：背景：肱骨近端骨折手术后的急性感染率尚不清楚。这项研究的目的是报告肱骨近端骨折治疗后的发病率并分析感染的危险因素。材料和方法：我们报告了452例肱骨近端骨折的回顾性多中心研究。通过使用单变量和/或线性回归分析对数据进行建模以确定比值比（OR）。逻辑回归分析用于检查人口统计学特征和其他特征，并可能混淆危险因素与感染之间的真实关联。结果：平均年龄为62.1岁，其中314例为女性。在这些患者中，有18名（4％）患有急性感染。与感染相关的因素包括手术时间（OR，1.009; P = .05），术前使用葡萄糖酸氯己定的皮肤准备（OR，0.13; P = .008）和预防性抗生素（OR，10.73; P = .03） ）。手术延迟几乎达到了显着水平（OR，1.71; P = .06）。结论：这项研究表明，用葡萄糖酸氯己定洗肩，避免使用第一代头孢菌素，而采取更有效的预防措施，可以有效降低肱骨近端骨折治疗后的感染风险。

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