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首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >Clinical systematic observation of Kangxin capsule curing vascular dementia of senile kidney deficiency and blood stagnation type.
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Clinical systematic observation of Kangxin capsule curing vascular dementia of senile kidney deficiency and blood stagnation type.

机译：康欣胶囊治疗老年性肾虚血瘀型血管性痴呆的临床系统观察。

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摘要

OBJECTIVE: To observe the validity and safety of Kangxin capsule curing the patients with vascular dementia (VaD). PATIENTS AND METHODS: Fifty-six patients with vascular dementia of kidney deficiency and blood stagnation type were selected on the basis of defined diagnostic criteria and were randomly divided into Kangxin group (29) and control group (27), observing the relevant accumulation scores in dementia scale before and after treatment and changes of endothelin (ET), sex hormone, immunity and routine examinations. RESULTS: Kangxin capsule can effectively improve the symptom of patients with VaD of senile kidney deficiency and blood stagnation type, and the average value of curative effect index of 29 patients in the treatment group is 23.01>/=20%, i.e. effective; compared with that before treatment, both CD(4) and CD(4).CD(8)(-1) rises (P<0.05) after the treatment with Kangxin capsule; for the male VaD patients of the Kangxin group, T level increases (P<0.05) and estrodial (E(2)).testerone (T)(-1) value decreases (P<0.05) after the treatment; for the female VaD patients of the Kangxin group, E(2), E(2).T(-1) value increases a great deal (P<0.05) compared with that before treatment; ET level of both groups decreased on average (P<0.01), and did not demonstrate any obvious toxic side effect. CONCLUSIONS: Kangxin capsule is a valid and safe preparation of Chinese traditional medicine for curing VaD of senile kidney deficiency and blood stagnation type.
机译：目的：观察抗心胶囊治疗血管性痴呆（VaD）的有效性和安全性。病人与方法：根据明确的诊断标准，选择56例肾虚性血管性痴呆伴血瘀型患者，随机分为康新组（29例）和对照组（27例），观察其相关蓄积评分。治疗前后的痴呆量表以及内皮素（ET），性激素，免疫力和常规检查的变化。结果：康欣胶囊能有效改善老年性肾虚VaD，血瘀型患者的症状，治疗组29例疗效指数的平均值为23.01> / = 20％，即有效。康欣胶囊治疗后CD（4）和CD（4）.CD（8）（-1）均较治疗前增加（P <0.05）。康新组男性VaD患者治疗后T水平升高（P <0.05），而雌激素水平降低（E（2））。睾丸激素（T）（-1）降低（P <0.05）。康新组女性VaD患者的E（2），E（2）.T（-1）值较治疗前增加了很多（P <0.05）;两组的ET水平平均下降（P <0.01），且未显示任何明显的毒副作用。结论：康欣胶囊是治疗老年肾虚血瘀型VaD的有效，安全的中药制剂。

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