...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >Traditional Tongan cures for morning sickness and their mutagenic/toxicological evaluations.
【24h】

Traditional Tongan cures for morning sickness and their mutagenic/toxicological evaluations.

机译：传统的汤加治愈晨吐及其诱变/毒理学评估。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Every year millions of women become pregnant, and more than 60% of them will develop some form of morning sickness. Yet drugs like Thalidomide, Bendectin and other possibly potent teratogens administered for pre-partum nausea have severely limited any medicinal intervention. In Tonga, women have been treated for morning sickness for hundreds of years. Two types of traditional treatments exist, the first one consists of an infusion of fresh leaves, commonly called vai momoko. The second type of treatment is called vai haka, which is made from the boiled bark of several trees. In this paper we describe the results of 6 months of intensive interviews in Tonga regarding the second type of treatment called vai haka. In addition, we tested vai haka for mutagenic and teratogenic effects. Data from the Ames TA-98 mutagenic bioassay clearly indicate that vai haka is not mutagenic with or without S-9 activation. Twenty-six experimental CD-1 white mice were gavaged with 0.1 ml of vai haka (at 540xthe human dose) while the control group of 17 mice were gavaged with 0.1 ml of water to determine teratogenic and developmental effects of the vai haka. No significant teratogenic or developmental anomalies occurred in the mice dosed with vai haka compared to the controls.
机译：每年都有数以百万计的妇女怀孕，其中超过60％的妇女会出现某种形式的孕吐。然而，用于产前恶心的药物如Thalidomide，Bendectin和其他可能有效的致畸剂，已严重限制了任何药物干预。在汤加，妇女接受晨吐治疗已有数百年历史。存在两种类型的传统疗法，第一种是注入新鲜的叶子，通常称为vai momoko。第二种处理方法叫做vai haka，它是由几棵树的煮沸的树皮制成的。在本文中，我们描述了在汤加进行的为期6个月的密集访谈的结果，该访谈涉及第二种称为vai haka的治疗。此外，我们测试了vai haka的诱变和致畸作用。来自Ames TA-98诱变生物测定的数据清楚地表明，无论是否经过S-9活化，vai haka都不诱变。 26只实验性CD-1白色小鼠被灌胃0.1 ml的vai haka（以人类剂量的540倍），而对照组的17只小鼠则被灌胃0.1 ml的水以确定vai haka的致畸和发育作用。与对照组相比，在服用vai haka的小鼠中没有发生明显的致畸或发育异常。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号