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Clinical Effects of Anterior Cerebral Artery Infarction

机译:前脑动脉梗死的临床疗效

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摘要

Anterior cerebral artery infarction is uncommon. We studied the topographical distribution of the lesions and the resulting clinical effects for a better understanding of their relationship and the functional outcome. There were 17 patients; the mean age of the cohort was 71 years. There were 10 men and 7 women. Two clinical syndromes were identified in accordance to the two anatomic areas of distribution. The paracentral lobule syndrome (group 1) was characterized by contralateral motor weakness, the leg more than the arm. The second group involved mainly the motor and supplementary motor areas. Beside contralateral weakness, they had a clinical picture of extrapyramidal symptomatology, which was designated as pseu-doparkinsonian syndrome (group 2). Sixty percent of the patients in group 2 had bilateral occlusive carotid artery disease compared with 14% in the group 1, and it is likely that the mechanism was artery-to-artery embolism or cardioembolism in this group. In group 1, the lesions were smaller but superficial and it is possible that small emboli from the heart or parent large artery caused the obstruction. The location of the occlusion may be indicative of the stroke mechanism. The pseudopar-kinsonian group with extrapyramidal features attributable to involvement of the supplementary motor area had an unfavorable outcome. There was poor correlation between size of the infarct and functional outcome (P = .12) in both groups.
机译:脑前动脉梗塞并不常见。我们研究了病变的地形分布及其产生的临床效果,以更好地了解其关系和功能结局。有17例患者。该队列的平均年龄为71岁。男10例,女7例。根据两个解剖分布区域确定了两个临床综合征。中央小叶旁综合征(第1组)的特征是对侧运动无力,腿多于手臂。第二组主要涉及运动和辅助运动领域。除了对侧无力外,他们还有锥体外系症状的临床表现,被称为假性-帕金森综合征(第2组)。第2组中有60%的患者患有双侧闭塞性颈动脉疾病,而第1组中只有14%的患者,该机制很可能是该组的动脉-动脉栓塞或心脏栓塞。在第1组中,病变较小但浅表,并且可能是来自心脏或父大动脉的小栓子引起阻塞。闭塞的位置可以指示中风机制。具有锥体外系特征的假par-kinsonian组归因于辅助运动区的累及,其结果不理想。两组梗死面积与功能结局之间的相关性均较弱(P = .12)。

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