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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Magnetic Resonance Perf usion Imaging in Acute Middle Cerebral Artery Stroke: Comparison of Blood Volume and Bolus Peak Arrival Time
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Magnetic Resonance Perf usion Imaging in Acute Middle Cerebral Artery Stroke: Comparison of Blood Volume and Bolus Peak Arrival Time

机译：急性中脑动脉中风的磁共振波成像：血容量和血浆峰值到达时间的比较

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摘要

Ten patients with a diagnosis of acute middle cerebral artery stroke were evaluated using perfusion magnetic resonance imaging (MRI) during bolus injection of gadolinium diethylenetriaminepentaacetic acid (GdDTPA), MR angiography, and conventional MRI, Scans were performed within 24 hours of symptoms onset, and 5 of the 10 patients had follow-up MR scans 3 or more days later to determine radiological outcome. Perfusion data were analyzed in terms of relative regional cerebral blood volume (rCBV) and bolus peak arrival times (BAT). Although relative rCBV values overall showed no significant changes compared with contralateral regions of interest, BAT was significantly increased in both infarct and peri-infarct regions. Areas of abnormal BAT significantly exceeded areas of T-2 hyperintensity in acute studies; follow-up images indicated that the size of infarction increased to include some regions with previously abnormal BAT. BAT appears to be a more sensitive parameter for the detection of abnormal cerebral perfusion than rCBV. Used in conjunction with other MR methods, perfusion MR imaging may allow visualization of ischemic tissue at risk of infarction in acute stroke.
机译：在推注injection二亚乙基三胺五乙酸（GdDTPA），MR血管造影和常规MRI的过程中，使用灌注磁共振成像（MRI）评估了10例诊断为急性中脑动脉中风的患者，在症状发作后24小时内进行了扫描， 10例患者中有5例在3天或更长时间后进行了MR随访，以确定放射学结果。根据相对区域脑血流量（rCBV）和推注峰值到达时间（BAT）分析灌注数据。尽管总体上相对rCBV值与对侧感兴趣区域相比无明显变化，但在梗塞区域和梗塞周围区域，BAT均显着增加。在急性研究中，异常BAT的面积显着超过了T-2高强度区域。随访图像表明，梗死面积增大，包括了先前有异常BAT的某些区域。与rCBV相比，BAT对于检测异常脑灌注似乎是更敏感的参数。与其他MR方法结合使用时，灌注MR成像可以使急性卒中中有梗塞风险的缺血组织可视化。

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