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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Hypoalbuminemia predicts acute stroke mortality: Paul Coverdell Georgia Stroke Registry.
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Hypoalbuminemia predicts acute stroke mortality: Paul Coverdell Georgia Stroke Registry.

机译：低白蛋白血症可预测急性中风死亡率：Paul Coverdell乔治亚州中风登记处。

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BACKGROUND: Mortality remains unacceptably high among patients hospitalized for acute stroke. Additional knowledge about factors that contribute to mortality after stroke is important for instituting therapies to lower mortality. We sought to determine the factors that predict mortality in patients hospitalized for acute stroke. METHODS: In all, 1477 consecutively admitted patients with acute stroke in 34 hospitals in the state of Georgia participating in the Paul Coverdell Georgia Stroke Registry during a 3-month period (December 1, 2001-February 28, 2002) were identified by retrospective chart review using primary or secondary International Classification of Diseases, Ninth Revision codes. Of patients, 31% were black, 65% were white, and 58% were women. We determined inhospital mortality after admission for acute stroke in this representative group of patients. RESULTS: There were 154 (10%) inhospital deaths among the 1477 patients admitted with acute stroke. Univariate analysis showed that mortality was associated with older age (P = .0008), stroke type (P = .0051), Glasgow Coma Scale score less than 9 (P < .0001), decreased serum albumin (P = .0001), elevated creatinine (P = .0067), and elevated blood glucose (P = .0063). In the multivariate analysis, independent risk factors for mortality after acute stroke included older age (P = .004), stroke type (P = .0007), Glasgow Coma Scale score less than 9 (P < .0001), and decreased serum albumin (P = .0003). There was no relationship between race and inhospital mortality (P = .9041). In addition, there was no association between independent predictors and race. CONCLUSION: In addition to previously recognized predictors of inhospital mortality, we found hypoalbuminemia to be an independent predictor of mortality in a biracial cohort of patients with acute stroke.
机译：背景：在因急性中风住院的患者中，死亡率仍然很高。有关中风后导致死亡的因素的其他知识对于建立降低死亡率的疗法很重要。我们试图确定预测住院急性卒中患者死亡率的因素。方法：通过回顾性图表确定了在3个月内（2001年12月1日至2002年2月28日）在乔治亚州的34家医院参加Paul Coverdell乔治亚中风注册中心的1477例连续入院的急性中风患者。使用主要或次要的《国际疾病分类》第九修订版进行审核。在患者中，黑人占31％，白人占65％，女性占58％。我们确定了该代表性患者中急性卒中的住院后死亡率。结果：在接受急性卒中的1477例患者中，有154例（10％）住院死亡。单因素分析显示，死亡率与年龄较大（P = .0008），中风类型（P = .0051），格拉斯哥昏迷量表评分小于9（P <.0001），血清白蛋白降低（P = .0001），肌酐升高（P = .0067），血糖升高（P = .0063）。在多变量分析中，急性卒中后死亡的独立危险因素包括年龄较大（P = .004），卒中类型（P = .0007），格拉斯哥昏迷量表评分小于9（P <.0001）和血清白蛋白降低（P = .0003）。种族与住院死亡率之间没有关系（P = .9041）。此外，独立的预测因素与种族之间没有关联。结论：除先前公认的院内死亡率预测因素外，我们发现低白蛋白血症是急性卒中患者的混血儿队列中死亡率的独立预测因素。

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