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Causes of ischemic stroke in young adults in Thailand: a pilot study.

机译:泰国年轻人中风缺血性中风的原因:一项初步研究。

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摘要

There is scarce information about ischemic stroke in young adults in Thailand. The purpose of this study was to explore the causes of ischemic stroke in Thai adults age 16-50 years. All ischemic strokes treated in persons in this age range between August 2006 and December 2008 were prospectively included. Stroke subtypes were classified according to Trial of ORG 10172 in Acute Stroke Treatment criteria as large-artery atherosclerosis (LAA), cardioembolism (CE), small-artery occlusion (SAO), stroke of other determined cause (OC), or stroke of undetermined cause (UND). The study group comprised 99 patients, with a mean age of 40 years and a mean National Institutes of Health Stroke Scale score of 8. In patients age <41 years, UND (32%; P = .0652) and OC (30%; P = .0167) were the most common stroke subtypes. In patients age 41-50 years, SAO (29%; P = .0947) and UND (21%) were the most common subtypes. Antiphospholipid syndrome (6%) and neurosyphilis (4%) were the leading causes of the OC subtype. Hyperlipidemia, smoking, and hypertension were common risk factors. Although the distribution of stroke subtypes was comparable with that found in previous studies from other countries, the identified causes were different.
机译:在泰国,有关年轻人中风的信息很少。这项研究的目的是探讨泰国16至50岁成年人中缺血性中风的原因。前瞻性地包括了2006年8月至2008年12月在该年龄段人群中治疗的所有缺血性中风。根据ORG 10172试验在急性中风治疗标准中将中风亚型分类为大动脉粥样硬化(LAA),心脏栓塞(CE),小动脉闭塞(SAO),其他确定原因的中风(OC)或不确定的中风原因(UND)。该研究组包括99名患者,平均年龄为40岁,美国国立卫生研究院卒中量表评分平均为8。在年龄小于41岁的患者中,UND(32%; P = .0652)和OC(30%; P = .0167)是最常见的中风亚型。在41-50岁的患者中,SAO(29%; P = .0947)和UND(21%)是最常见的亚型。抗磷脂综合征(6%)和神经梅毒(4%)是OC亚型的主要原因。高脂血症,吸烟和高血压是常见的危险因素。尽管中风亚型的分布与其他国家先前的研究相当,但确定的原因却不同。

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