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Long-term Survival of Older Australian Women with a History of Stroke

机译:有中风病史的澳大利亚老年妇女的长期生存

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Background: Although many people survive an initial stroke, little is known about long-term impacts of stroke on survival. Methods: Data from the Australian Longitudinal Study on Women's Health were used to compare 12-year survival rates in older women with prevalent stroke, incident stroke, and no stroke. Cox regression models were fitted to assess the effect of lifestyle and demographic characteristics on the relationship between stroke and all-cause mortality. The "no stroke" group was used as the reference category in all statistical models. Results: At baseline, 4% of the women reported a previous stroke (prevalent stroke). At survey 2 in 1999, a further 3% reported having a stroke between 1996 and 1999 (incident stroke). Stroke was significantly associated with reduced long-term survival. Age-adjusted hazards ratios (HRs) were: 1.64 (1.43-1.89) for the "prevalent stroke" group and 2.29 (1.97-2.66) for the "incident stroke" group. Adjusting for comorbidities reduced the HRs, but the risk of death was still significantly higher in the 2 stroke groups. Adjusting for demographic and lifestyle factors did not make any further difference to the relationship between stroke and survival. However, obesity and past smoking were also risk factors for mortality. Conclusions: This study highlights the long-term impacts of stroke on life expectancy and the importance of comorbidities and other lifestyle factors in affecting poststroke survival.
机译:背景:尽管许多人在中风后得以幸存,但对中风对生存的长期影响知之甚少。方法:使用澳大利亚妇女健康纵向研究的数据比较患有中风,中风和无中风的老年女性的12年生存率。拟合Cox回归模型以评估生活方式和人口统计学特征对中风与全因死亡率之间关系的影响。在所有统计模型中,“无中风”组均用作参考类别。结果:基线时,有4%的妇女报告过先前的中风(流行中风)。在1999年的调查2中,又有3%的人报告在1996年至1999年之间患有中风(事件性中风)。中风与长期生存率降低显着相关。年龄调整后的危险比(HRs)为:“中风”组为1.64(1.43-1.89),“事故中风”组为2.29(1.97-2.66)。调整合并症可降低HR,但在2个卒中组中,死亡风险仍显着较高。调整人口统计学和生活方式因素对中风和生存之间的关系没有任何进一步的影响。但是,肥胖和过去吸烟也是死亡的危险因素。结论:这项研究强调了中风对预期寿命的长期影响以及合并症和其他生活方式因素在影响中风后生存中的重要性。

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