...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Chlamydia pneumoniae is a Likely Risk Factor for Ischemic Stroke in Young Patients
【24h】

Chlamydia pneumoniae is a Likely Risk Factor for Ischemic Stroke in Young Patients

机译：肺炎衣原体是年轻患者缺血性中风的危险因素

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Recently, Chlamydia pneumoniae has been identified as a risk factor for atherosclerosis, cardiovascular disease, and stroke, In young patients the causes of stroke are more diverse, and remain unknown in about 30% of cases, despite thorough investigations. To find a possible relationship between C pneumoniae infection and stroke at young age, we investigated C pneumoniae antibody titers in 41 patients with ischemic stroke who were younger than 50 years old and in 55 healthy control subjects. A positive IgA antibody titer to C pneumoniae was significantly associated with stroke (crude odds ratio 2.1; 90% confidence interval 1.1-9.5; P = .04), After adjusting for hypertension, smoking, and hypercholesterolemia, positive Chlamydia antibodies remained associated with stroke (adjusted odds ratio 2.8; 90% confidence interval 1.1-7.1; P = .04). No significant association between positive IgG antibodies and stroke was found. Because a positive IgA antibody titer may reflect a persistent infection, these data indicate that persistent C pneumoniae infection may be an independent risk factor for stroke at young age.
机译：最近，肺炎衣原体已被确定为动脉粥样硬化，心血管疾病和中风的危险因素。尽管进行了详尽的研究，但在年轻患者中，中风的病因更为多样，在约30％的病例中仍然未知。为了发现年轻时肺炎C感染与中风之间的可能关系，我们调查了41名50岁以下的缺血性中风患者和55名健康对照者的肺炎C抗体滴度。肺炎衣原体的IgA抗体滴度阳性与中风显着相关（粗机优势比2.1; 90％置信区间1.1-9.5; P = .04）。在调整了高血压，吸烟和高胆固醇血症后，衣原体抗体阳性仍与中风相关（调整后的优势比2.8; 90％置信区间1.1-7.1; P = .04）。阳性IgG抗体与中风之间未发现明显关联。由于IgA抗体滴度阳性可能反映了持续性感染，因此这些数据表明持续性肺炎C感染可能是年轻时中风的独立危险因素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号