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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Mechanical Ventilation in Ischemic Stroke
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Mechanical Ventilation in Ischemic Stroke

机译：缺血性卒中的机械通气

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Objective: Coma or respiratory failure in patients with acute ischemic stroke (IS) may require mechanical ventilation (MV). The inclusion criteria used in previous studies on MV for patients with stroke have been very heterogeneous. We carried out this prospective study in our neurologic stroke and intensive care department to assess clinical and radiologic features, mortality, outcome, and prognosis factors for patients presenting with acute IS involving the middle cerebral artery (MCA) and requiring MV. Methods: Of 470 patients admitted with acute IS involving the MCA territory, we prospectively enrolled 50 patients requiring MV. Indications for intubation were a Glasgow coma score <10 or respiratory failure. Results: The survival at 1 year was 30%. The mortality (70%) was independent of the reason for ventilation, Survivors had a mean Barthel index of 59 (+-) 25 and a mean modified Rankin score of 4 (+-) 1. Logistic regression showed that survivors were characterized by incomplete MCA territory involvement and atherosclerosis origin. Conclusion: Patients with MCA IS who require MV have high mortality regardless of the cause of intubation. Survival is associated with incomplete MCA territory involvement and atherosclerosis origin.
机译：目的：急性缺血性中风（IS）患者的昏迷或呼吸衰竭可能需要机械通气（MV）。先前关于卒中患者的MV研究中使用的纳入标准非常不同。我们在我们的神经系统卒中和重症监护室进行了这项前瞻性研究，以评估表现为涉及脑中动脉（MCA）并需要MV的急性IS患者的临床和放射学特征，死亡率，结局和预后因素。方法：在470例涉及MCA领域的急性IS入院患者中，我们前瞻性招募了50例需要MV的患者。插管的指征是格拉斯哥昏迷评分<10或呼吸衰竭。结果：1年生存率为30％。死亡率（70％）与通气原因无关，幸存者的平均Barthel指数为59（+-）25，平均兰金改良评分为4（+-）1。Logistic回归显示，幸存者的特征是不完全MCA领土受累和动脉粥样硬化的起源。结论：无论插管原因如何，需要MV的MCA IS患者均具有较高的死亡率。生存与MCA区域参与不完全和动脉粥样硬化起源有关。

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