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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Intracranial versus Extracranial Artery Dissection Cases Presenting with Ischemic Stroke
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Intracranial versus Extracranial Artery Dissection Cases Presenting with Ischemic Stroke

机译：颅内与颅外动脉夹层合并缺血性中风的病例

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Background: To compare the clinical and radiologic characteristics, possible stroke mechanisms, and prognosis of intracranial artery dissections (IADs) with those of extracranial artery dissections (EADs) presenting with cerebral infarction. Methods: Among 3250 adult patients with acute ischemic stroke (cerebral infarction), we prospectively recruited and categorized patients with cerebral infarction secondary to spontaneous cerebral artery dissection into IAD or EAD groups. The clinical and radiologic characteristics, possible stroke mechanisms according to the distributions of the infarctions based on diffusion-weighted imaging, and prognosis were analyzed for both groups. Results: There were 48 and 50 patients experiencing IAD and EAD, accounting for 1.5% and 1.5% of all ischemic stroke patients, respectively. Compression of the perforating artery was the most common possible stroke mechanism (33.3%) in IADs; thromboembolism was more common in EADs than that in IADs (36 of 50 versus 12 of 48; P < .001). Magnetic resonance imaging and angiography were used to investigate the arterial dissections in all IAD patients and 46 EAD patients. Based on magnetic resonance imaging and angiography, the IADs more frequently displayed dissecting aneurysm (6 of 48 versus 0 of 46; P = .027) and intimal flap or double lumen (21 of 48 versus 4 of 46; P < .001) than EADs. For the clinical characteristics and prognosis, there was no significant difference between the 2 groups. Conclusions: These results indicate that IAD is an important cause of ischemic stroke, and it displays unique radiologic characteristics and specific stroke mechanisms compared with EAD.
机译：背景：为了比较临床表现和影像学特征，可能的中风机制以及颅内动脉夹层（IAD）与脑梗死伴发的颅外动脉夹层（EAD）的预后。方法：在3250名成人急性缺血性卒中（脑梗死）患者中，我们前瞻性将自发性脑动脉夹层继发的脑梗死患者分为IAD或EAD组。对两组的临床和影像学特征，根据梗塞分布的可能的卒中机制（基于弥散加权成像）以及预后进行了分析。结果：分别有48例和50例发生IAD和EAD的患者，分别占所有缺血性中风患者的1.5％和1.5％。在IAD中，穿支动脉的压迫是最常见的中风机制（33.3％）。在EAD中，血栓栓塞比在IAD中更为普遍（50中的36比48中的12; P <.001）。磁共振成像和血管造影用于调查所有IAD患者和46例EAD患者的动脉夹层。基于磁共振成像和血管造影，IAD较解剖性动脉瘤（48个中的6个相对于0个中的46个; P = .027）和内膜瓣或双腔内膜（48个中的21个与46个中的4个; P <.001）更频繁地显示EAD。对于临床特征和预后，两组之间无显着差异。结论：这些结果表明IAD是缺血性中风的重要原因，与EAD相比，它具有独特的放射学特征和特定的中风机制。

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