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Cerebral Small-Vessel Disease in Neuro-Behcet Disease

机译:脑-贝塞特病的脑小血管疾病

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Background: Involvement of central nervous system is very common in Behcet disease, known as neuro-Behcet disease (NBD). However, there have been few reports which evaluated stroke-like cerebral small-vessel disease associated with Behcet disease. Objective: We evaluated cerebral small-vessel lesions by using magnetic resonance imaging in 2 patients with NBD. Clinical Cases: In a 41-year-old woman case, who developed dysarthria and left hemiparesis, diffusion-weighted images (DWI) showed small high-intensity areas in the bilateral internal capsule. The right lesion had a low apparent diffusion coefficient (ADC) value, whereas the left one had a high value. In a 59-year-old woman case, who developed dysarthria and left hemi-hypesthesia, DWI showed high-intensity areas in the right side of the pons and in the right peduncle of the midbrain. The lesion in the pons had a low ADC value, whereas the lesion in the midbrain had a high value. ADC map may be useful to identify symptomatic lesions in the brain, because only the lesions with low ADC values were symptomatic. Conclusions: NBD should be considered in those who had not had any risk factors for ischemic stroke but experienced cerebral small-vessel disease. (C) 2015 by National Stroke Association
机译:背景:中枢神经系统受累在Behcet病(称为神经-Behcet病(NBD))中非常普遍。然而,很少有报道评估与白塞氏病相关的中风样脑小血管疾病。目的:我们通过磁共振成像评估了2例NBD患者的脑小血管病变。临床病例:在一名41岁女性病例中,发生构音障碍和左偏瘫,弥散加权图像(DWI)在双侧内囊中显示出小的高强度区域。右病变的表观扩散系数(ADC)值低,而左病变的表观扩散系数(ADC)值高。在一名59岁的女性病例中,发生构音障碍并左半身感觉减退,DWI在脑桥的右侧和中脑的右花梗上显示出高强度区域。脑桥病变的ADC值较低,而中脑病变的ADC值较高。 ADC图可能有助于识别脑部症状性病变,因为只有具有较低ADC值的病变才是症状性的。结论:对于没有缺血性卒中危险因素但经历过脑小血管疾病的患者,应考虑NBD。 (C)国家卒中协会2015年

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