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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Predictive Factors for the Spontaneous Recanalization of Large and Middle Cerebral Arteries after Acute Occlusion
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Predictive Factors for the Spontaneous Recanalization of Large and Middle Cerebral Arteries after Acute Occlusion

机译：急性闭塞后大中脑动脉自发再通的预测因素

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Objective: This study aims to investigate the predictive factors for the spontaneous recanalization of occluded arteries in patients with acute ischemic stroke. Methods: A total of 139 patients with consecutive acute ischemic stroke were enrolled from June 2010 to June 2013. The clinical and biochemical parameters were measured in each participant. Occlusion and recanalization of the carotid artery, the middle cerebral artery, and the vertebral and basilar arteries were identified by using computed tomographic angiography or digital subtraction angiography. Results: Among the 139 patients, 23 showed spontaneous recanalization, whereas 116 did not. In the patients with spontaneous recanalization, the proportion of atrial fibrillation was significantly lower (0% versus 29.31%, P = .01), whereas the proportion of stage 3 hypertension was significantly higher (60.87% versus 32.76%, P = .01) than that of those without recanalization. Logistic regression analysis showed that the proportion of atrial fibrillation was negatively (odds ratio [OR]: .117, 95% confidence interval [CI]: .015-.918, P = .04) associated with spontaneous recanalization, whereas the proportion of stage 3 hypertension was positively (OR: 4.316, 95% CI: 1.533-12.154, P = .01) associated with it. Conclusions: Atrial fibrillation is associated with reduced spontaneous recanalization of the large and middle cerebral arteries in patients after acute ischemic stroke-induced occlusion, whereas stage 3 hypertension may contribute to the promotion of the recanalization.
机译：目的：本研究旨在探讨急性缺血性卒中患者自发闭塞动脉再通的预测因素。方法：2010年6月至2013年6月，共139例连续性急性缺血性卒中患者入组。对每位参与者的临床和生化指标进行了测量。颈动脉，大脑中动脉以及椎动脉和基底动脉的阻塞和再通通过计算机断层血管造影或数字减影血管造影确定。结果：在139例患者中，有23例表现出自发性再通，而116例则没有。在自发性再通的患者中，房颤的比例显着降低（0％比29.31％，P = 0.01），而三期高血压的比例显着更高（60.87％对32.76％，P = 0.01）。比那些没有再通的人。 Logistic回归分析显示，房颤发生率与自发性再通相关，为负数（赔率[OR]：.117，95％置信区间[CI]：.015-.918，P = .04），而与3期高血压呈正相关（OR：4.316，95％CI：1.533-12.154，P = 0.01）。结论：心房纤颤与急性缺血性中风诱发的闭塞后大中脑动脉自发性再通减少有关，而3期高血压可能有助于再通。

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