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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Primary Pontine Hemorrhage in the Acute Stage: Clinical Features and a Proposed New Simple Scoring System
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Primary Pontine Hemorrhage in the Acute Stage: Clinical Features and a Proposed New Simple Scoring System

机译：急性期原发性庞廷出血：临床特征和建议的新的简单评分系统

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Background: It is important to evaluate the likelihood of fatality in patients with acute primary pontine hemorrhage (PPH) in emergency departments. We aimed to evaluate the clinical symptoms and computed tomography findings of PPH to develop a simple grading scale for predicting the mortality of PPH. Methods: Records of 101 consecutive patients admitted to our hospital with acute PPH between June 1, 2006, and January 31, 2014, were retrospectively reviewed. Independent predictors of 30-day mortality were identified by univariate and multivariate logistic regression analyses. A simple and easy clinical score (PPH score) was developed from independent factors to predict mortality in acute PPH. The PPH score was compared with the established intracerebral hemorrhage (ICH) score, which served as the reference scoring system. Results: Overall mortality rate 30 days after onset was 58.4% (59 of 101). Factors independently associated with 30-day mortality were Glasgow Coma Scale (GCS) score of 6 or less (P = .0051), absence of pupillary light reflex (P = .0003), and blood glucose of 180 mg/dL or greater (P = .0312). The PPH score was the sum of independent factors, which were assigned 1 point each. The area under the receiver operating characteristic curve for predicting 30-day mortality was .90 (95% confidence interval [CI], .84-.95) for PPH score and .86 (95% CI, .78-.93) for ICH score. Conclusions: GCS score of 6 or less, absence of pupillary light reflex, and plasma glucose of 10 mmol/L or greater are independent mortality predictors of PPH. The PPH score is a simple and reliable clinical grading scale for predicting 30-day mortality.
机译：背景：在急诊科中评估急性原发性桥脑出血（PPH）患者死亡的可能性很重要。我们旨在评估PPH的临床症状和计算机断层扫描结果，以开发出简单的分级量表来预测PPH的死亡率。方法：回顾性分析2006年6月1日至2014年1月31日间本院收治的101例急性PPH患者的病历。通过单因素和多因素logistic回归分析确定30天死亡率的独立预测因素。从独立因素发展出简单易行的临床评分（PPH评分）以预测急性PPH的死亡率。将PPH评分与既定的脑出血（ICH）评分进行比较，以作为参考评分系统。结果：发病后30天的总死亡率为58.4％（101之59）。与30天死亡率独立相关的因素是格拉斯哥昏迷量表（GCS）评分为6或更低（P = .0051），瞳孔无光反射（P = .0003）和血糖为180 mg / dL或更高（ P = .0312）。 PPH得分是独立因素的总和，每个独立因素得分为1分。 PPH评分的接收者工作特征曲线下可预测30天死亡率的面积为0.90（95％置信区间[CI] ，. 84-.95），对于PPH评分为0.86（95％CI，.78-.93）。 ICH分数。结论：GCS评分为6或更低，瞳孔无光反射以及血浆葡萄糖为10 mmol / L或更高是PPH的独立死亡率预测指标。 PPH评分是用于预测30天死亡率的简单而可靠的临床评分量表。

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