...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Intracranial Atherosclerosis and Poststroke Depression in Chinese Patients with Ischemic Stroke
【24h】

Intracranial Atherosclerosis and Poststroke Depression in Chinese Patients with Ischemic Stroke

机译：中国缺血性卒中患者的颅内动脉粥样硬化和中风后抑郁

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Intracranial atherosclerosis (ICAS) is a common etiology of ischemic stroke in Chinese patients, probably leading to regional hypoperfusion in the brain. The purpose of this prospective study was to investigate the association between ICAS and poststroke depression in Chinese patients with ischemic stroke. Methods: During the study period, a total of 569 patients aged between 40 and 80 years with acute ischemic stroke were consecutively admitted and screened. Patients with a National Institutes of Health Stroke Scale (NIHSS) total score of 15 or higher, with severe cognitive impairment, or with a history of depression before stroke were excluded. Two hundred seven patients with ischemic stroke were consecutively recruited in the study. Depressive symptoms were assessed in the acute stage and 3 months after stroke. Poststroke depression was defined as a score of 8 or higher in the 24-item Hamilton Depression Rating Scale. The evaluation of the magnetic resonance imaging scans focused on infarctions, white matter lesions, brain atrophy, and ICAS. Results: In the acute stage of stroke, logistic regression revealed that female sex, NIHSS score at admission, prestroke insomnia, and ICAS were significant predictors of poststroke depression. At 3 months after stroke, prestroke insomnia, the Mini-Mental State Examination score and ICAS were significant predictors of poststroke depression. Conclusions: ICAS may be a significant independent predictor of poststroke depression in Chinese patients with ischemic stroke. (C) 2016 National Stroke Association. Published by Elsevier Inc. All rights reserved.
机译：背景：颅内动脉粥样硬化（ICAS）是中国患者缺血性中风的常见病因，可能导致大脑局部灌注不足。这项前瞻性研究的目的是研究中国缺血性卒中患者ICAS与卒中后抑郁之间的关系。方法：在研究期间，共收治了569例年龄在40至80岁之间的急性缺血性中风患者。美国国立卫生研究院卒中量表（NIHSS）总分为15或更高，严重认知障碍或卒中前有抑郁史的患者被排除在外。该研究连续招募了207名缺血性中风患者。在急性期和中风后3个月评估抑郁症状。脑卒中后抑郁定义为24项汉密尔顿抑郁量表中的得分为8分或更高。磁共振成像扫描的评估重点是梗死，白质病变，脑萎缩和ICAS。结果：在中风的急性期，逻辑回归显示女性，入院时的NIHSS评分，中风前失眠和ICAS是中风后抑郁的重要预测指标。中风后3个月，中风前的失眠，小精神状态检查得分和ICAS是中风后抑郁的重要预测指标。结论：ICAS可能是中国缺血性卒中患者卒中后抑郁的重要独立预测因子。 （C）2016年全国中风协会。由Elsevier Inc.出版。保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号