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首页> 外文期刊>Journal of studies on alcohol and drugs. >Family History of Problem Drinking Is Associated With Less Sensitivity of Alcohol Demand to a Next-Day Responsibility
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Family History of Problem Drinking Is Associated With Less Sensitivity of Alcohol Demand to a Next-Day Responsibility

机译：问题饮酒的家族史与酒精需求对次日责任的敏感性降低有关

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Objective: Behavioral economic demand curves measure alcohol consumption as a function of price and may capture clinically relevant individual differences in alcohol-reinforcing efficacy. This study used a novel, behavioral-economic, hypothetical demand-curve paradigm to examine the association between family history of alcohol misuse and individual differences in both alcohol demand and the relative sensitivity of alcohol demand to next-day responsibilities. Method: Participants were 207 college students (47% male, 68.5% White, 27.4% African American, M_(age) =19.5 years) who reported at least one heavy drinking episode (5/4 or more drinks on one occasion for a man/woman) in the past month and completed two versions of an alcohol purchase task (APT) that assessed hypothetical alcohol consumption across 17 drink prices. In one APT (standard), students imagined they had no next-day responsibilities, and in the other, they imagined having a 10:00 a.m. test the next day. Results: A series of analyses of covariance indicated that participants with at least one biological parent or grandparent who had misused alcohol reported similar levels of alcohol demand on the standard APT but significantly less sensitivity to the next-day academic responsibility as measured by the percentage of reduction in demand intensity and breakpoint across the no-responsibility and next-day-test conditions. Conclusions: These findings provide initial evidence that APTs might clarify one potential mechanism of risk conferred by family history. Young adult heavy drinkers with a family history of problematic drinking may be less sensitive to next-day responsibilities that might modulate drinking in drinkers without a family history of alcohol problems.
机译：目的：行为经济需求曲线衡量酒精消费与价格之间的关系，并可能反映出酒精增强功效的临床相关个体差异。这项研究使用一种新颖的，行为经济学的假设性需求曲线范式来研究酗酒的家族史和酗酒需求的个体差异之间的关联，以及酗酒对次日职责的相对敏感性。方法：参与者为207名大学生，他们报告至少一次重度饮酒（男性一次饮酒5/4次以上），其中大学生为47％，白人为68.5％，白人为27.4％，美国M_（年龄）= 19.5岁。 /女士），并完成了两个版本的酒精购买任务（APT），该任务评估了17种饮料价格中的假设酒精消费量。在一项APT（标准）中，学生想象他们没有第二天的职责，而在另一项中，他们想象第二天上午10:00进行测试。结果：一系列的协方差分析表明，至少有一名生物学父母或祖父母滥用酒精的参与者对标准APT的酒精需求水平相近，但对第二天学业责任的敏感性明显降低（以降低无责任和次日测试条件下的需求强度和断点。结论：这些发现提供了初步证据，表明APT可能阐明了家族史赋予的一种潜在风险机制。有严重饮酒家族史的年轻成年重度饮酒者对第二天的责任可能不太敏感，后者可能会在没有饮酒家族史的饮酒者中调节饮酒。

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