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首页> 外文期刊>Journal of submicroscopic cytology and pathology >Morphological effects on the hard palatine mucosa of Calomys callosus submitted to experimental chronic alcoholism.
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Morphological effects on the hard palatine mucosa of Calomys callosus submitted to experimental chronic alcoholism.

机译：形态上的影响对Calomys os的硬p黏膜进行实验性慢性酒精中毒。

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摘要

The morphological effects of ethanol ingestion on the hard palatine mucosa of adult male Calomys callosus were observed. Twenty rodents were divided into two experimental groups: the control group received solid diet, Purina rat chow, and tap water ad libitum; the alcoholic group received the same solid diet and ethanol P.A. diluted 20% in water (v/v). After 270 days of treatment, all animals were sacrificed and the hard palatine mucosa were prepared for TEM and SEM methods. The epithelial cells of the alcoholic group showed some alterations like cytoplasmatic lipid droplets, pycnotic nucleus and increased mitochondrial size. The lamina propria also presented intense lipid droplets accumulation. The morphological changes suggested that chronic ethanol consumption was able to modify the integrity of the mucosa.
机译：观察到乙醇摄入对成年雄性卡洛斯call的硬ala黏膜的形态学影响。将二十只啮齿动物分为两个实验组：对照组接受固体饮食，Puria大鼠食物和任意自来水;对照组接受纯饮食。酒精组接受相同的固体饮食和乙醇P.A.用水稀释20％（v / v）。治疗270天后，处死所有动物，并准备好硬p肠黏膜用于TEM和SEM方法。酒精组的上皮细胞表现出一些改变，如胞质脂质滴，脓性核和线粒体大小增加。固有层也表现出强烈的脂质液滴积聚。形态变化表明，长期饮酒能够改变粘膜的完整性。

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