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首页> 外文期刊>Journal of the American Pharmacists Association: JAPhA >Boceprevir, telaprevir, and rilpivirine hydrochloride.
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Boceprevir, telaprevir, and rilpivirine hydrochloride.

机译：Boceprevir，telaprevir和rilpivirine盐酸盐。

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摘要

Hepatitis C virus (HCV) infection is characterized by inflammation of the liver, which can lead to reduced liver function and liver failure. The infection can develop in a number of ways, including exposure to blood that is infected with the virus, being born to a mother with HCV, having a sexual relationship with an infected person, sharing a needle, sharing personal items such as a razor or toothbrush with someone who is infected, and using unsterilized tattoo or piercing instruments. After the initial infection with HGV, most people develop chronic HCV infection. Many patients with the infection do not experience symptoms until liver damage occurs, which may take several years. Some develop cirrhosis of the liver, which can lead to liver damage with complications such as bleeding, jaundice, fluid accumulation in the abdomen, infections, and/or liver cancer. Liver disease resulting from HCV infection is the most frequent reason for which liver transplants are needed by patients in the United States.
机译：丙型肝炎病毒（HCV）感染的特征是肝脏发炎，可导致肝功能下降和肝衰竭。感染可以通过多种方式发展，包括暴露于感染了病毒的血液，由患有HCV的母亲所生，与被感染者有性关系，共用针头，共用诸如剃须刀或剃须刀之类的个人物品。与感染者一起使用牙刷，并使用未经消毒的纹身或穿孔工具。最初感染HGV后，大多数人会发展成慢性HCV感染。许多感染患者在出现肝损害之前不会出现症状，这可能需要几年时间。有些会发展为肝硬化，从而导致肝损害，并伴有诸如出血，黄疸，腹部积液，感染和/或肝癌等并发症。 HCV感染引起的肝病是美国患者最需要肝移植的最常见原因。

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