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首页> 外文期刊>Journal of the American Pharmacists Association: JAPhA >Concordance among three self-reported measures of medication adherence and pharmacy refill records.
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Concordance among three self-reported measures of medication adherence and pharmacy refill records.

机译：三种自我报告的药物依从性和药房笔芯记录之间的一致性。

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OBJECTIVE: To evaluate the level of agreement among three previously validated self-reported medication adherence measures and pharmacy refill records (RRs). DESIGN: Cross-sectional study. SETTING: Five primary care physician office sites in rural northeast Georgia. PARTICIPANTS: 139 adult patients with one or more of these chronic diseases: hypertension, diabetes mellitus, hypercholesterolemia, hypothyroidism, or a condition requiring hormone replacement therapy. INTERVENTIONS: Study participants completed the Brief Medication Questionnaire (BMQ), the Medication Adherence Survey (MAS), and the Medical Outcomes Study (MOS) instruments; pharmacy RRs for the medication or medications being used to treat the target disease were obtained from pharmacies used by the study participants. MAIN OUTCOME MEASURES: Adherence to medication therapy for target disease. RESULTS: Participants were nearly all white (98.6%), consistent with the Appalachian area in which the study was conducted, and mostly women (71.9%). While 91.4% of study participants reported taking their study medication most or all of the time, RRs showed mean adherence rates of 82.6%, 82.1%, 79.1%, 74.6%, and 69.8% for diabetes mellitus, hypertension, hypothyroidism, hypercholesterolemia, and hormone replacement therapy, respectively. Moderate correlations of .234, .261, and .213 were found between RRs and the MAS, MOS, and BMQ belief screen, respectively. Spearman correlations ranged from .091 between RRs and the BMQ regimen subscale to .313 between MOS and MAS. Pearson chi-square tests showed that only the BMQ belief subscale was significant in this study. CONCLUSION: Because of the weak to moderate concordance found among validated measures of adherence, the selection of a useful adherence measure in pharmacy practice is difficult. These findings underscore the difficulty in both assessing patients' medication-taking behavior and assessing and comparing the results of adherence research. The development of valid and reliable measures for easily assessing medication adherence behavior in community pharmacies is needed.
机译：目的：评估三项先前已验证的自我报告的药物依从性措施和药房笔录（RR）之间的一致性水平。设计：横断面研究。地点：乔治亚州东北部农村地区的五个初级保健医师办公室。参加者：139名患有以下一种或多种慢性疾病的成年患者：高血压，糖尿病，高胆固醇血症，甲状腺功能减退或需要激素替代疗法的疾病。干预措施：研究参与者完成了简要药物调查问卷（BMQ），药物依从性调查（MAS）和医学结果研究（MOS）仪器;从研究参与者使用的药房获得用于治疗目标疾病的一种或多种药物的药房RR。主要观察指标：坚持针对目标疾病的药物治疗。结果：参加者几乎全部是白人（98.6％），与进行研究的阿巴拉契亚地区一致，大部分为女性（71.9％）。尽管91.4％的研究参与者报告了大部分或全部时间都在服用研究药物，但RRs显示糖尿病，高血压，甲状腺功能低下，高胆固醇血症和糖尿病的平均依从率分别为82.6％，82.1％，79.1％，74.6％和69.8％。激素替代疗法。 RR与MAS，MOS和BMQ信念筛选之间分别发现了0.234，.261和.213的适度相关性。 Spearman相关性的范围从RR和BMQ方案子量表之间的.091到MOS和MAS之间的.313。皮尔逊卡方检验表明，只有BMQ信念分量表在这项研究中是重要的。结论：由于在经过验证的依从性措施中发现弱至中度的一致性，因此在药房实践中很难选择有用的依从性措施。这些发现突出了评估患者服药行为以及评估和比较依从性研究结果的难度。需要开发有效和可靠的措施来轻松评估社区药房的药物依从性行为。

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