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Pharmacotherapy of hospitalised hiv-infected patients in a general hospital during 1990,1997 and 2001

机译：1990年，1997年和2001年在综合医院住院感染HIV的患者的药物治疗

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Objective: To describe the changes over time in drag therapy (antiretroviral as well as co-administered drugs) in HIV-infected patients who required hospital-isation during the period 1990-2001.In addition, we wanted to evaluate and compare the characteristics of these patients.Design/setting: Retrospective review of hospitalisations of HIV-infected patients in a general hospital.Results: During specified periods in 1990,1997 and 2001, 22 patients out of 130 outpatients, 29 out of 394 outpatients, and 19 out of 570 outpatients, respectively, who were treated at the outpatient clinic were admitted 30, 38 and 27 times, respectively.The mean duration of these hospitalisations was 18.8,14.2 and 16.7 days, respectively.The percentage of women and the mean age of the hospitalised patients increased over the studied time period.AIDS-related diagnoses de creased when comparing 1997 with 2001.The type of co-administered drugs of patients who required hospitalisation was fairly stable, but the total volume (defined as the mean volume of drugs per patient per bed-day) increased dramat ically from 5.3 in 1990 to 6.8 in 1997 and to 15.5 in 2001.Dual and triple antiretroviral therapy decreased and became quadruple or greater therapy when 1997 and 2001 were compared.In addition, the number of hospitalised patients not treated with antiretroviral drugs increased from 1997 to 2001.Conclusion: The incidence of hospital admissions decreased but the volume of co-administered drugs increased from 1990 to 2001, suggesting extensive co-morbidity in the patients who still require hospitalisation.
机译：目的：描述1990-2001年期间需要住院治疗的HIV感染患者的药物治疗（抗逆转录病毒药物和共同给药药物）随时间的变化。我们还想评估和比较设计/设置：对综合医院中感染HIV的患者的住院治疗进行回顾性审查。结果：在1990、1997和2001年的特定时期，130名门诊患者中有22名患者，394名门诊患者中有29名患者，19名患者中有19名患者分别在门诊就诊的570名门诊患者分别接受了30次，38次和27次入院，这些住院的平均时间分别为18.8、14.2和16.7天，女性所占百分比和平均住院年龄在研究期间，患者数量有所增加。与1997年相比，与艾滋病相关的诊断与2001年相比有所下降。需要住院的患者的联合用药类型相当稳定，但总容量（定义为每位患者每天床位的平均药物量）从1990年的5.3急剧增加到1997年的6.8和2001年的15.5。双重和三重抗逆转录病毒疗法减少，在1997年和2001年变为四重或更大剂量此外，1997年至2001年未接受抗逆转录病毒药物治疗的住院患者人数有所增加。结论：1990年至2001年住院人数减少但合并用药量增加，表明该地区广泛合并症。仍需要住院的患者。

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