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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >Epileptiform EEG spikes and their functional significance.
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Epileptiform EEG spikes and their functional significance.

机译：癫痫样脑电图钉及其功能意义。

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摘要

Field potentials detected in the space surrounding cellular elements of the nervous system are essential in the diagnosis of epileptic seizures. This article describes the elementary mechanisms underlying the generation of field potentials and the special functional conditions leading to epileptiform field potentials. Primary transmembranous currents generate secondary ional currents along the cell membranes in intra- and extracellular compartments. The portion of these currents that flows through the brain tissue to the cortical surface can be detected as field potentials. A high synchronization of these field potentials is needed to induce brain signals. Field potentials recorded during epileptic activity are based on alterations in neuronal membrane potentials. Paroxysmal depolarization shift has proved to be characteristic in the epileptiform activity of individual neurons. Epileptiform field potentials are generated in functionally different structures with different elementary mechanisms. In focal convulsive activity limited to the cortex, the surface potential does not necessarily reflect the bioelectrical events in deeper cortical laminae and can be interrupted in different ways. The discrepancy between superficial EEG potentials and neocortical output may be the basis for dissociation between EEG signals and clinical signs.
机译：在神经系统细胞元件周围的空间中检测到的场电势对于癫痫发作的诊断至关重要。本文介绍了场电位产生的基本机制以及导致癫痫样场电位的特殊功能条件。初级跨膜电流在细胞内和细胞外区室中沿着细胞膜产生次级离子流。可以将流过大脑组织到皮质表面的这些电流的一部分检测为场电势。这些场电势需要高度同步以诱导大脑信号。在癫痫活动期间记录的场电位是基于神经元膜电位的变化。阵发性去极化移动已被证明是单个神经元癫痫样活动的特征。癫痫样场电位在具有不同基本机理的功能不同结构中产生。在局限在皮层的抽搐活动中，表面电势不一定反映更深的皮层中的生物电事件，可以以不同的方式中断。表层脑电势与新皮质输出之间的差异可能是脑电信号与临床体征分离的基础。

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