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Recognizing a mother's voice in the persistent vegetative state.

机译:在持续的植物状态下识别母亲的声音。

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We studied an 8-year-old boy after a near-drowning left him in a vegetative state (VS) for 4 years before the study. Findings fulfilled all clinical criteria for the diagnosis of VS. The purpose of this study was to investigate whether there was significant differential activation of the brain in response to hearing his mother's voice compared with the voices of unknown women. The data were assessed using quantitative electric tomography (QEEGt), a technique that combines anatomical information of the brain by MRI with EEG patterns to estimate the sources of the EEG within the brain. We found significant differences for EEG frequencies from 14-58 Hz, with a peak at 33.2 Hz (gamma band). The 3D reconstruction showed that these statistical differences were localized in the lateral and posterior regions of the left hemisphere. No significant differences were found between unknown women vs. basal conditions. These results demonstrate recognition of the mother's voice and indicate high-level residual linguistic processing in a patient meeting clinical criteria for VS. These findings launch new ethical and practical implications for the management of VS patients.
机译:在研究之前,我们研究了一个8岁男孩的昏昏欲睡状态,使他处于植物人(VS)状态。研究结果满足了诊断VS的所有临床标准。这项研究的目的是调查与不知名女性的声音相比,在听到母亲的声音时大脑是否有明显的差异激活。使用定量电子断层扫描(QEEGt)评估数据,该技术将MRI的大脑解剖学信息与EEG模式结合在一起,以估计大脑中EEG的来源。我们发现,EEG频率在14-58 Hz之间存在显着差异,在33.2 Hz(伽马频带)处出现一个峰值。 3D重建显示这些统计差异位于左半球的外侧和后侧。未知妇女与基础状况之间没有发现显着差异。这些结果证明了对母亲声音的识别,并表明了满足VS临床标准的患者中的高级残余语言处理能力。这些发现为VS患者的治疗带来了新的伦理和实践意义。

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