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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >Rostral anterior cingulate cortex activity in the theta band predicts response to antidepressive medication.
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Rostral anterior cingulate cortex activity in the theta band predicts response to antidepressive medication.

机译：θ带的前额扣带回皮层活动预测了对抗抑郁药物的反应。

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摘要

During the last 10 years the knowledge about rostral anterior cingulate cortex (ACC) activity in major depression has substantially increased. Several groups have independently described a relationship between resting activity in this area and response to antidepressant treatment. We have recently confirmed a relationship between resting activity of rostral ACC activity and response in a group of 20 patients with major depression using resting theta activity. In this earlier study regions of interest (ROI) were defined in order to establish regional specificity. Differences between responders and nonresponders were only found in the ACC-ROI, but not in the posterior cingulate region. We have now reanalyzed our data using a whole brain voxelwise approach, in order not to miss any other relevant functional differences. In addition to major differences between responders and nonresponders in the rostral ACC, we have identified a nearby region in the midline orbito-frontal region.
机译：在过去的十年中，有关严重抑郁症中的延髓前扣带回皮层（ACC）活动的知识已大大增加。几个小组独立地描述了该区域的静息活动与抗抑郁治疗反应之间的关系。最近，我们证实了一组20名重度抑郁症患者的静息theta活性，其鼻翼ACC活性的静息活动与反应之间存在关联。在此较早的研究中，定义了感兴趣的区域（ROI）以建立区域特异性。反应者和非反应者之间的差异仅在ACC-ROI中发现，而在后扣带区域中未发现。现在，我们已经使用全脑体素方法重新分析了我们的数据，以免遗漏任何其他相关的功能差异。除了在鼻尖ACC的反应者和非反应者之间的主要差异外，我们还确定了中线眶额区的附近区域。

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