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首页> 外文期刊>Clinical nephrology >Depression and health-related quality of life in maintenance hemodialysis patients.
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Depression and health-related quality of life in maintenance hemodialysis patients.

机译：维持性血液透析患者的抑郁与健康相关的生活质量。

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BACKGROUND: This study was designed to determine the prevalence of depression among hemodialysis (HD) patients from urban hospitals in Korea, to illustrate demographic factors and biomarkers associated with depression and health-related quality of life (HRQOL), and to demonstrate association between depression and HRQOL. PATIENTS AND METHODS: For this multicenter, cross-sectional study, 160 HD patients from 3 university teaching hospitals and 3 local dialysis units in Korea were enrolled. Korean Beck's depression inventory and Korean version of Kidney Disease Quality of Life short form, version 1.3 (KDQOL-SFTM 1.3) were used to evaluate depression and quality of life, respectively. RESULTS: Depression was found in 51 out of 160 (31.9%) patients. Old age (> 60 years old), low hemoglobin level (< 10 g/dl), and low economic status were associated with depression, and old age (OR 6.138, p = 0.001) was the most important risk factor among them. Old age, female gender, presence of diabetes mellitus, high comorbidity index score (modified Charlson comorbidity index > or = 6), hypoalbuminemia (< 4.0 g/dl), and high CRP (> 0.5 mg/dl) were common factors associated with decreased HRQOL. Depression and HRQOL showed inverse linear relationship. CONCLUSIONS: Moderate to severe depression was common in maintenance HD patients in Korea. Among factors associated with depression and decreased HRQOL, some characteristics are potentially modifiable by social and medical intervention. Further prospective studies are warranted to see whether depression and HRQOL can be improved by modifying these factors.
机译：背景：这项研究旨在确定韩国城市医院血液透析（HD）患者的抑郁症患病率，阐明与抑郁症和健康相关的生活质量（HRQOL）相关的人口统计学因素和生物标志物，并证明抑郁症之间的关联和HRQOL。患者与方法：这项多中心，横断面研究纳入了来自韩国3所大学教学医院和3个当地透析单位的160名HD患者。使用韩贝克的抑郁量表和韩版肾脏疾病生活质量简短版本1.3（KDQOL-SFTM 1.3）来评估抑郁和生活质量。结果：160例患者中有51例（31.9％）患有抑郁症。老年（> 60岁），血红蛋白水平低（<10 g / dl）和经济状况低下与抑郁症相关，而老年（OR 6.138，p = 0.001）是其中最重要的危险因素。老年，女性，糖尿病的存在，合并症指数高（修正的Charlson合并症指数>或= 6），低白蛋白血症（<4.0 g / dl）和高CRP（> 0.5 mg / dl）是与以下疾病相关的常见因素HRQOL降低。抑郁与HRQOL呈反线性关系。结论：在韩国维持HD患者中常见中度至重度抑郁。在与抑郁症和HRQOL降低有关的因素中，某些特征可能会通过社会和医疗干预而改变。有必要进行进一步的前瞻性研究，以观察通过改变这些因素是否可以改善抑郁症和HRQOL。

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