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Factors in the interictal record predicting an ictal episode: a case study.

机译:发作期记录中预测发作发作的因素:一个案例研究。

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This report deals with a patient with intractable seizures, who had 64 subdural electrodes implanted onto the left frontal and temporal cerebral cortex in anticipation of probable seizure surgery. One specific region on the left frontal lobe proved to be the focus for both the interictal spikes and also for the ictal activity. Our goal was to determine what electrical characteristics in the interictal record predicted the ictal episodes. The number of interictal spikes and also the amount of fast activity (15-128/sec) progressively increased before each of the 5 ictal episodes; an analysis showed that the number of spikes and their frequency proved the more significant variable. One other characteristic that changed before the ictal episodes was a great decrease in the interval between spikes as an example of a diminishing variability or increasing periodicity. Thus, the important factors in the interictal record that lead to an ictal event are the number of spikes, the amount of fast activity and the decreasing variability between the spikes.
机译:该报告涉及一名患有顽固性癫痫发作的患者,该患者因预期可能发生癫痫手术而在左额叶和颞叶大脑皮层植入了64个硬膜下电极。左额叶上的一个特定区域被证明是发作间期峰值和发作活动的焦点。我们的目标是确定间质记录中的哪些电学特征预示了发作。在5次发作之前,发作高峰的数量以及快速活动的数量(15-128 /秒)逐渐增加。分析表明,尖峰的数量及其频率证明是更显着的变量。在发作发作之前改变的另一个特征是尖峰之间的间隔大大减小,例如变异性减小或周期性增加。因此,在发作记录中导致发作事件的重要因素是尖峰的数量,快速活动的数量以及尖峰之间的可变性降低。

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